Covidpocalypse Now: an update

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Most of the Covid news is about vaccines.

A second vaccine has passed the final non-red tape hurdle in the US, and will likely be authorized by the end of the week. Six million doses will be distributed, probably over the weekend or early in the week, to over 3,000 locations.

There is argument and discussion going on as to the lower age limit on the vaccines. So far everything seems authorized for 18 year olds and older. It will probably be a serious mistake if that isn’t adjusted very soon. Now, the kids who transmit the disease that kill grandma are anonymous. Once they are the main carriers, they will not be, and a spotty subgroup of an entire generation will be scarred. At least, we’ll be given by fate the name for that generation. The Marys (for Typhoid Mary).

Let’s talk about Pregnant and lactating women for a minute. There have been no systematic trials pertaining to pregnant women, so the FDA advice is vague. They say, “you decide.” The following are supportable facts:

1) There is evidence, subject to revision because it is not the focus of any systematic experimental study, that pregnant women are somewhat protected from getting Covid-19, but not to anywhere near the degree that they can flout caution.

2) There is evidence, again subject to revision, that when pregnant women do get Covid-19, they have a number of worse outcomes than other people of similar age. They may get sicker, and there is a possible risk of preterm birth.

3) Non-live vaccines are generally considered safe for pregnant women.

To manufacturers and health care providers, this may be more a mater of blame and liability than anything else. Of all the people who get the vaccine, some are going to get sick or die randomly even if the vaccine never causes an actual problem, and someone is going to sue somebody over something. The chance of such a suit winning probably goes up if the plaintiff is a pregnant woman or her survivors, or if a baby is born with a problem etc. etc. So, by saying “you decide” we just get on with it, is probably the thinking.

VERY IMPORTANT: We humans have a lot of misconceptions about immunity and pregnancy. A common falsehood is that immunity of the mother is passed on to the offspring. This is not true. Also, an in utero fetus does not get vaccinated when the mother gets vaccinated. A lot of people believe these things happen but they do not.

What does happen is that the mother’s immune products, if she’s got them, circulate in the fetus, and may even be found in the newborn for a while. But an infant does not have much of a functioning adaptive immune system, so there can be no development of long term immunity, and the magical immunity stuff we have spent so much time talking about can’t be passed on.

During lactation, some of this humeral immunity of the mother will be shared with the offspring via breast feeding. This, of course, is also temporary.

It has been a while since I’ve done a literature search on this, but last time I looked there were no studies that really examined how effective any of this passive immunity is. Our cultural love of breastfeeding, and rhetoric from pro-breast feeding organizations, have led many people to believe that mother to infant immunity (i.e. through breastfeeding and esp the passing on of colostrum) is powerful and highly effective. We don’t really know this.

Doses:

In the US right now 2.9 million Pfizer doses (with second doses already accounted for) have been shipped. Moderna will ship over 5 million doses right away. According to Health and Human Services (a Trump Crime Family Joint) there will be enough doses to vaccinate everybody in the US by the end of June 2021. We await the replacement of the Deplorables with Biden appointees to confirm (or deny) that.

Can you pass Covid-19 on if you are vaccinated?

Nobody knows yet, but there is not really a useful “yes” or “no” answer to this. Here’s the story: What matters is the R0 value of the disease, right? How many people will get infected down the road if a particular individual is infected. More realistically, sort of, imagine a population of 1 million people, and 1,000 people freshly infected show up and there are no precautions taken. If that disease is Covid and the 1 million are not vaccinated, the next “generation” of infection will see more than 1,000 people infected, and the next generation, more than that, etc. as a wave of the disease spreads across the populations. SO, maybe, 1,000 gets you 1800, and that gets you 2500, and that gets you 4,800, and so on.

If most everybody is vaccinated, the whole point is that the chance of the virus being able to reproduce in you at all is lower, the time frame and intensity of that reproduction is shorted or lowered. Maybe to zero, but even if not, the R0 value is significantly lowered.

So, in the above scenario, with the population mainly vaccinated, 1,000 infected people gets you maybe 100 (max, that would b a lot) which gets you 10, which gets you zero, and Bob’s your uncle.

Have you read the breakthrough novel of the year? When you are done with that, try:

In Search of Sungudogo by Greg Laden, now in Kindle or Paperback
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3 thoughts on “Covidpocalypse Now: an update

  1. Some Republican lawyers and Covid-19.

    In December, Abbott – backed by Texas attorney general Ken Paxton – went so far as to encourage businesses in Austin to thwart a local curfew and ring in the new year late into the night.

    Emboldened crowds gathered outside of open bars. Inside, revelers danced and hugged while bartenders went maskless, a deadly recipe for the surge upon a surge that health experts warned would happen if Americans didn’t stay home for the holidays.

    Meanwhile, Bankhead-Kendall has watched as patients who survived even mild or asymptomatic Covid-19 cases deal with collapsed lungs or blood clots, likely because of the virus.

    Texas governor’s hands-off approach to Covid-19 has allowed the virus to thrive

    A bloody disgrace, Abbott and Paxton should be charged with crimes against humanity.

    1. Yes, there should be consequences for the actions by the right all the way up and down the ladder. But as we’ve seen, for the right consequences are only appropriate for “others”: women, the poor, minorities…

      A data point: When was the last time you saw rickA or mikeN take any responsibility for the lies and racist crap they spew?

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