I don’t, and a couple of months ago I decided I probably wouldn’t, because of apparent possible connection to Russian hacking.
Check this out:
There is absolutely nothing to see here.
I don’t, and a couple of months ago I decided I probably wouldn’t, because of apparent possible connection to Russian hacking.
Check this out:
There is absolutely nothing to see here.
I did some research on mice, and I thought I’d pass it on. First, though, let me suggest that you get some of this stuff. Use it to paint a symbol on each of your wireless mice that matches a symbol on each of your mice dongles. It will help keep you sane. You’ll still find yourself constantly in possession of mice and dongles that do not match, but at least they will have these pretty little symbols you drew all over them.
There is some interesting and exciting stuff going on with mice.
The Logitech MX Anywhere 2 Wireless Mobile Mouse, Long Range Wireless Mouse is over fifty bucks, but it has some excellent features. It is small and portable and normative in shape and design. It works on any surface, is highly precise, nice to use, all that. It is a Laser tracking mouse. It has an internal rechargeable battery.
This mouse uses a small USB dongle or bluetgooth (Bluetooth Smart Ready). You can pair up to three different devices. It has hyper-speed scrolling.
There are several mice in this category ranging across price. One of them is the Logitech MX Anywhere 2S Wireless Mouse with FLOW Cross-Computer Control and File Sharing for PC and Mac – 910-005132, which is close to 80 bucks, and is like the MX Anywhere 2, but has the additional magical capability of controlling multiple devices, including managing a cross-device clipboard. You pair the mouse up with each computer, then you tie it into the same local network both computers are on. Here’s a video from Logitech:
This supposedly works on Linux, Macs and Windows.
I am suspicious of the whole ergonomic thing. Ergonomic, in mice and similar devices, seems to be “we fit your hand so well you will only move one or two muscles ever,” which seems a bad idea. I think a mouse should require more movement and adjustment by the hand in order to Not cause repetitive motion syndrome. Note that this is entirely my non-expert opinion and I may be quite wrong.
Anyway, one of the top rated and coolest Ergonomic mice is probably the Anker 2.4G Wireless Vertical Ergonomic Optical Mouse which is extreme in its design and intended to minimize RSS. The same company makes a variety of products, and note, these are generally not expensive.
The affordable Logitech M720 Triathalon Multi-Device Wireless Mouse pairs with multiple devices, has fancy buttons, has hyper fast scrolling capability, and uses a single AA battery. It uses bluetooth.
The Logitech M330 Silent Plus Wireless Large Mouse is a large size mouse that makes no noise and is inexpensive (and wireless, but not bluetooth)
The super accruate, wired, Corsair Gaming M65 Pro RGB FPS Gaming Mouse, Backlit RGB LED, 12000 DPI, Optical is for gamers and has lots of buttons.
The mouse I need is probably the one I hope to find over at Goodwill; I need a plug in USB mouse to allow quick access to any computer any time without needing a dongle dangling off the back of something.
And the cops cheered.
Trump gave a talk to a gathering of police out on Long Island, earlier today. It went horribly. There are cops that are going to take Trump’s lead, take what he said seriously, and because of that, they are going to harm or kill Americans and end their own careers, destroying their own families and parts of their communities along the way.
The President of the United States egged the police on to disdain their civilian bosses, and they cheered him. The President of the United States told the police that they should not avoid harming suspects, and they clapped. The President of the United States encouraged the police to injure suspects, and they cheered.
He called American citizens being harassed by the police “animals.”
This was like and unlike Trump’s over-the-top and embarrassing tirade in front of the Boy Scouts. Similar because this was in both cases Trump being an unmitigated and stupid ass. But different because even though both the cops and the Boy Scouts were blindly cheering and clapping and yowling at these obnoxious comments, we could guess that the leaders of the Boy Scouts were potentially embarrassed. Also, for every Boy Scout there is one or more parental unit of some kind, and we knew many of them would be upset about Trump’s yammerings. And that all turned out to be true, and the Boy Scouts eventually, after some pressure, apologized.
But with the cops we should not assume anything like this is true. The only thing worse than a bunch of cops that show up to hassle some citizens is an organized bunch of cops in the form of an association or union. Today, Trump empowered the police, as a faction on our increasingly fractionated society, to become more violent. I don’t think there is any doubt that they will do this.
The New York City police department did not attend the Long Island event. Some see this as a boycott, since New York is a sanctuary city, and Trump intends to crack down on sanctuary cities. But it is not clear what the position of the New York City, or any other police department or group of police is. As far as I can tell, Trump’s new violence is something cops love. You should see the happy glowing faces of the cops standing behind the president when he tells them to treat suspects like animals, knock their heads on their cruisers, and otherwise, hurt them.
Happy glowing faces of cops clapping and cheering because they just got permission from the head of the United States to be physically harm American citizens.
I have been looking for the name of the organization that sponsored this talk, but I haven’t been able to find it. Whatever organization that is, we should demand that they apologize for Trump’s speech. But they won’t. Because they are cops.
Today is also the day that Donald Trump fired his Chief of Staff and replaced him with the Director of Homeland Security. The top security officer, in a sense, the top cop, of the country is now, apparently, at least according to a set of tweets, going to also be the person closest to the President in any official capacity in the West Wing. I wonder who thought of that idea?
Think about that for a minute. This is what dictators do.
Watch Chris Hays alter the anatomy of a Republican Congress member:
Donald Trump has consulted with his generals and military experts …
After consultation with my Generals and military experts, please be advised that the United States Government will not accept or allow……
— Donald J. Trump (@realDonaldTrump) July 26, 2017
and declared that Transgender individuals will not be allowed to serve in the US Military in any capacity because the Military has other things to do
….Transgender individuals to serve in any capacity in the U.S. Military. Our military must be focused on decisive and overwhelming…..
— Donald J. Trump (@realDonaldTrump) July 26, 2017
which apparently includes world domination will will be disrupted by the burden of transgenderness.
….victory and cannot be burdened with the tremendous medical costs and disruption that transgender in the military would entail. Thank you
— Donald J. Trump (@realDonaldTrump) July 26, 2017
We’ll see.
If you give your children over to the Boy Scouts for a day or two, they may do something to them akin to abuse. This happened.
The Boy Scouts knew what they were getting into when they invited Donald Trump to speak at their national event. They even posted warnings for the troop leaders and scouts, on their blog.
As a unit leader or staff member, you can help make the president’s visit a success by ensuring that any reactions to the president’s address are, as we state in our Scout Law, friendly, courteous, and kind. This includes understanding that chants of certain phrases heard during the campaign (e.g. “build the wall,” “lock her up”) are considered divisive by many members of our audience, and may cause unnecessary friction between individuals and units. Please help us ensure that all Scouts can enjoy this historical address by making sure that your troop members are respectful not only of the president, but of the wide variety of viewpoints held by Scouts and Scouters in the audience tonight.
The speech was a travesty. It was rambling and foggy, the sort of thing that might make one worry about drug abuse or a brain problem. It was insulting to many people. It was inappropriate, including profanity and reference to sexual exploits of famous people (see below). It was dishonest, unfair, un-American, and stupid.
Many felt right away that the Boy Scouts should be asked to formally and publicly disavow the speech or make some sort of comment on what happened. For my part, I called the Northern Star Boy Scout office (that’s our regional Boy Scout thing) and complained. My friend Dave wrote this public letter:
Dear Boy Scouts of America,
During the Kennedy administration, I was a cub scout in Vienna, Austria, a city on the front line of the Cold War. Parts of that city, and nearly every other city in Europe, were still in ruins after the war ignited by an out-of-control demagogue placed in power by a minority of the voters. Part of my mother’s family had to flee their homes to America, while others were murdered by agents of that government.
That is why I forced myself to watch the current president’s speech to the Boy Scouts Jamboree in its entirety. It was a disgrace. It began with outright lies and accusations. (“The fake press will say there were 200 people here.”) It trashed his opponent, who was favored by more voters, though not by electoral tampering with the majority, and whom many Boy Scout parents must have voted for. It favored one religion over another. It used what at least used to be a swear word. It sowed divisiveness amongst Americans. It urged disrespect against a former President. It denigrated the nation’s government itself. It promoted its political campaign rhetoric and co-opted the audience into shouting its slogan.
According to the speaker, he is an honorary president of the Boy Scouts of America. I urge you to rescind that title.
I expect that as honorable officials of the Boy Scouts of America, you will issue a statement to all troops identifying the remarks that were inappropriate and did not conform to the Boy Scout regulations about politics.
Sincerely,
David J. Formanek
All the media, being fake and all, have gone after Trump (though I’m not sure about FOX news), and generally speaking, the reaction is strong and widespread. Even as this is happening, of course, Trump-trolls are scanning social media for anti-Trump comments, and complaining about how we are taking away Donald’s “free speech.” Which, of course, no one has done. We have the First Amendment right to complain about what the president says, and forces that intend to curtail that right are truly nefarious.
(Note: One item on a local FOX news page decries the comparison liberals are making between Hitler, the Hitler Youth, and Trump’s Boy Scout Speech. That comparison certainly has been made by many! I just watched the famous Hitler to the Youth speech (not the Hitler Youth, just German youth). The comparison is apt, but Hitler was a much more focused orator than Trump.)
Many parents of scouts, and many former scouts, reacted negatively to Trump’s speech and in many cases to the Scouts’ lack of good decision making and failure to take responsibility for the fiasco they knowingly created. See twitter examples below. The BSA, for its part, has as of this writing said nothing other than that they do these events and invite the presidents, so what?
Clearly, the Scouts, as an organization, are clueless, even if many of their members are still prying their jaws off the floor. They should know something about the Constitution by now, and recognize that Donald Trump is the greatest threat to it since Major General Sir George Prevost. After all, the Boy Scouts of America have been in a Constitutional fight or two.
In a five to four decision, the Supreme Court ruled that opposition to homosexuality is part of BSA’s “expressive message” and that allowing homosexuals as adult leaders would interfere with that message.
It is inappropriate to subject youth, especially in the context of an organization that desired to have no undesirables near their boys just in case, to the sort of Drek spewed by Donald Trump at this Jamboree. It is Orwellian, at best, to pretend nothing bad happened, that the Boy Scouts of America didn’t do something horribly wrong by inviting the profane and obnoxious pussy-grabber-in-chief to speak to their kids. The Boys Scouts of America have committed the unforgivable sin of pretending that nothing is wrong, that all is normal, of standing by while our Democracy burns, and perhaps, adding fuel to the fire.
My son will not be joining the Boy Scouts. What about yours?
@boyscouts,Trump's speech violated your own policy. My son didn't join the Scouts to be used as POTUS's political prop! https://t.co/O9gJmeZoz1
— Leila Rice (@Leila_A_Rice) July 25, 2017
The Internet is amazing. They've already translated Trump's entire Boy Scout speech from the original German.
— Sage_dude (@Sage_dude) July 25, 2017
As a Scout leader, my stomach is in knots about what Trump did today. If you haven't watched it yet, don't. It's downright icky.
— Chris Murphy (@ChrisMurphyCT) July 25, 2017
Who in the world makes menacing political speech at a BOY SCOUT JAMBOREE?!?
Oh, yeah. THAT guy. https://t.co/DI0YV0Wrwf— David Axelrod (@davidaxelrod) July 25, 2017
I served proudly as a Boy Scout in my youth. Trump has none of the virtues of a scout, and his speech to them was, like him, embarrassing.
— George Takei (@GeorgeTakei) July 25, 2017
‘These are our children!’ MSNBC host unloads on Trump over Boy Scout Jamboree speech https://t.co/q33aHT5xre
— Joe Hickman (@joehick58) July 25, 2017
Ex-CIA chief: Trump’s Boy Scout speech felt like "third world authoritarian's youth rally" https://t.co/uARXsO4Wo8 pic.twitter.com/uYFQtLLtCu
— The Hill (@thehill) July 25, 2017
I put this as an appendix because to get the full force of it all, you have to read a lot of rambling and offensive text and look stuff up in Wikipedia.
I remember growing up in New York State learning that William Levitt was famous for creating white suburbs developing land on Long Island and elsewhere in order to facilitate a white flight from increasingly non-white Manhattan. He may or may not have been involved in the conspiracy to keep public transit busses off Long Island because they were used by black folk to get to places like Coney Island. Anyway, from Wikipiedia:
Levitt refused to integrate his developments. The Jewish Levitt barred Jews from Strathmore, his first pre-Levittown development on Long Island in New York, and he refused to sell his homes to blacks. His sales contracts also forbade the resale of properties to blacks through restrictive covenants, although in 1957 a white couple resold their house to the first black family to live in a Levitt home. Levitt’s all-white policies also led to civil rights protests in Bowie, Maryland in 1963. The National Association for the Advancement of Colored People and the American Civil Liberties Union opposed Levitt’s racist policies, and the Federal Housing Administration prepared to refuse mortgages on his next Levittown. Nevertheless, Levitt would not back down and continued planning another whites-only Levittown in Willingboro Township, New Jersey. He fought legal challenges in New Jersey courts until the United States Supreme Court refused to hear his case.
Trump, also associated with promoting and renting segregated housing in New YOrk, went on a long tirade about how great Levitt was, and how the Scouts should aspire to be him.,
… When I was young there was a man named William Levitt. You have some here. You have some in different states. Anybody ever hear of Levittown?
And he was a very successful man, became unbelievable – he was a home builder, became an unbelievable success, and got more and more successful. [Note: Levitt was like Trump, went bankrupt and otherwise failed quite often at business.] And he’d build homes, and at night he’d go to these major sites with teams of people, and he’d scour the sites for nails, and sawdust and small pieces of wood, and they cleaned the site, so when the workers came in the next morning, the sites would be spotless and clean, and he did it properly. And he did this for 20 years, and then he was offered a lot of money for his company, and he sold his company, for a tremendous amount of money, at the time especially. This is a long time ago. Sold his company for a tremendous amount of money.
And he went out and bought a big yacht, and he had a very interesting life. I won’t go any more than that, because you’re Boy Scouts so I’m not going to tell you what he did.
[This may be a reference to Levitt’s divorse, affair with his secretary whom he later married, and his later affair and marriage with a french art dealer, but who knows. Maybe Trump knows more than just that. Anyway, Levitt might have been a fellow pussygrabber.]
Should I tell you? Should I tell you?
You’re Boy Scouts, but you know life. You know life.
So look at you. Who would think this is the Boy Scouts, right? So he had a very, very interesting life, and the company that bought his company was a big conglomerate, and they didn’t know anything about building homes, and they didn’t know anything about picking up the nails and the sawdust and selling it, and the scraps of wood. This was a big conglomerate based in New York City.
And after about a 10-year period, there were losing a lot with it. It didn’t mean anything to them. And they couldn’t sell it. So they called William Levitt up, and they said, would you like to buy back your company, and he said, yes, I would. He so badly wanted it. He got bored with this life of yachts, and sailing, and all of the things he did in the south of France and other places. You won’t get bored, right? You know, truthfully, you’re workers. You’ll get bored too, believe me. Of course having a few good years like that isn’t so bad.
[None of that is true. Levitt became the titular head of the company after he sold it, and it was even named after him, but he never re-owned it. Not that this matters; Just letting you know the alt-facts are flowing. Most of this story is incorrect, muddled, or made up.]
But what happened is he bought back his company, and he bought back a lot of empty land, and he worked hard at getting zoning, and he worked hard on starting to develop, and in the end he failed, and he failed badly, lost all of his money. He went personally bankrupt, and he was now much older. And I saw him at a cocktail party. And it was very sad because the hottest people in New York were at this party.
[Reminder: this is a speech to the Boy Scouts of America.]
It was the party of Steve Ross – Steve Ross, who was one of the great people. He came up and discovered, really founded Time Warner, and he was a great guy. He had a lot of successful people at the party.
And I was doing well, so I got invited to the party. I was very young. And I go in, but I’m in the real estate business, and I see a hundred people, some of whom I recognize, and they’re big in the entertainment business.
And I see sitting in the corner was a little old man who was all by himself. Nobody was talking to him. I immediately recognized that that man was the once great William Levitt, of Levittown, and I immediately went over. I wanted to talk to him more than the Hollywood, show business, communications people.
So I went over and talked to him, and I said, “Mr. Levitt, I’m Donald Trump.” He said, “I know.” I said, “Mr. Levitt, how are you doing?” He goes, “Not well, not well at all.” And I knew that. But he said, “Not well at all.” And he explained what was happening and how bad it’s been and how hard it’s been. And I said, “What exactly happened? Why did this happen to you? You’re one of the greats ever in our industry. Why did this happen to you?”
And he said, “Donald, I lost my momentum. I lost my momentum.” A word you never hear when you’re talking about success when some of these guys that never made 10 cents, they’re on television giving you things about how you’re going to be successful, and the only thing they ever did was a book and a tape. But I tell you – I’ll tell you, it was very sad, and I never forgot that moment.
And I thought about it, and it’s exactly true. He lost his momentum, meaning he took this period of time off, long, years, and then when he got back, he didn’t have that same momentum.
I’m so glad the Boy Scouts got to hear that inane and inaccurate story.
John McCain has a good heath care plan, and if has his way, you won’t.
The Senator most often accredited for thinking for himself (that’s a lie) will vote with Russian agent Donald Trump and the rest of the Republicans to take away Obama care. The moment he gets a chance.
However, he can’t right now because he is indisposed, recovering form surgery.
We at Greg Laden’s Blog wish Senator McCain a speedy recovery and hope he is well. But we also urge him to think about his privilege and not take access to the sort of health care he has from other Americans.
Speaking of the Russians, The Looking Glass War, the fourth George Smiley novel by John le Carré, in Kindle form, is currently and temporarily two bucks. Just thought you might like to add that to your collection.
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1776 by David McCullough is not a new book — it was published in 2006 — but I just got around to reading it, enjoyed it, and wanted to say a few words about it.
But first my David McCullough story.
You probably don’t know Scotty MacNeish (aka Richard Stockton MacNeish), but you should. He ended his illustrious career in a car accident in the field (in Belize, if I recall correctly) about 15 years ago, but many years before that he started out his career by discovering the origin of Maize, identifying its site of domestication and the timing of that important moment in Native American prehistory.
I had these two friends, back in graduate school, one of whom worked on the Franklin Expedition, the other ran Biosphere for a while. Anyway, they got married, and I was invited to the wedding. As a non-relative and roughly equal friend to both, I was seated at the reception table for odd balls, and had the pleasure of sharing that table with Scotty.
There were two or three others at the table, including a very well dressed and dapper middle aged gentleman who seemed to be fancy. But, since we were at a wedding reception at the 18th century home of the state’s largest lumbar barron, there was a lot of wealth around, so he wasn’t sticking out. But, Scotty, who is a bulldog populist with the sense of humor of a hyena, seemed to be going after the guy, putting him down (in a humorous way, mostly) and essentially, trying to cut him down to size for some reason.
Somewhere during the conversation, someone, not this gentleman and not Scotty as I recall, but someone else, mentioned the just released and highly popular documentary, “The Civil War” by Ken Burns. Surely, you know it. But, at the time, I’d only had a chance to see one or two episodes and it has been a while since I saw them. The gentleman at the table seemed to know something about the series, so I asked him, “Did you have something to do with the Civil War documentary?”
He looked at me for a moment. Everyone at the table looked at me. It was pretty obvious I had faux pas’ed all over myself. He grinned a little and said, “Young man, I am the Civil War.”
That was David McCullough. The guy who did the Civil War. Like this (starting about 1:40):
OK, so, now, about the book, 1776.
This is a book about a man, his army, and a year that he and they might like to mostly forget.
The American Revolution had roots back many decades before 1776, and the first actions of the war happened in 1775. 1776 started with the siege of Boston by Washington and his army, and it ends with Washington’s crossing of the Delaware to defeat the unsuspecting Hessian army.
One could argue that the evacuation of Boston by the British was a solid victory for the Patriots, but really, it was not so simple. One could argue that the crossing of the Delaware and defeat of the Hessians at Trenton was a solid victory for the Patriots, and that would be undeniably true, even if in the larger scheme it was a small victory compared to some other things that happened. In between these two events, almost everything that could go wrong went wrong. Reading the history of Washington’s army in that year, if you could do that without already knowing what ultimately happened, you can imagine any of a number of possible outcomes, none of which is an American victory over the British. And, the final event of the year, the victory in New Jersey, was not the kind of victory that changes the course of a war. If anything, it was just enough to decide not to give up yet.
I was generally aware of what happened that year. I’ve done a lot of work and research surrounding the American Revolution in New York and New England. I excavated the city burned during the battle of Bunker Hill, and did work along Paul Revere’s Ride (did not find hoof prints), and other Revolutionary war related localities in Massachusetts. I grew up visiting Fort George and Fort Ticonderoga in New York every few years, and I excavated on Phillip Schuyler’s grounds (you will know him as the father of Hamilton’s wife), and spent a fair amount of time in the vicinity of Saratoga (the decisive battle of that war). But, 1776 was not a rehash for me. First, it was not archaeological, but historical. Second, McCollough uses a lot of source material that had not been developed back when I was doing scholarly work in this area. Third, much of the story takes place in New York (the city) and although I’m from up river, it is not an area with Revolutionary War sites I’m familiar with.
American Revolutions: A Continental History, 1750-1804 is very well written. It is not dense or long, as many history books are, yet it is very well documented if you want to follow the footnotes. It is revealing of the real George Washington, who was probably a mixture of what you were thinking and some stuff you were not thinking, and it is also revealing of the nature of the Revolution itself, how close it was to failing, while at the same time, how inevitable it was to take a certain course. I recommend the book.
I read this book because I wanted to develop an updated perspective on that time, and this, I felt, would be a good segue from other things I’d been reading, and a good refresher. Next in line: American Revolutions: A Continental History, 1750-1804 by Taylor, followed by Alexander Hamilton
by Chernow.
First, a word about Arduino and why you should care. An Arduino is what is called a “prototyping micro-controller” aka “really fun electronic gizmo toy.”
Micro-controllers are everywhere. When you “turn on” a machine in your house, chances are there was already a micro-controller sitting there, running on a minute bit of juice from a built in battery, waiting for you to push a button. Then, you turned a dial or selected an option on your dishwasher, or changed the setting on your thermostat, or picked some alternative mode on your coffee pot, or shifted into a different gear using a “gear shift” in your fly-by-wire Prius, or you opened up the birthday card and cats meowed out “Happy Birthday.”
All of those events involved a micro-controller, which consists of thee parts. There is a brain inside it, there is a set of sensors or actuators (a thing that detects that the greeting card has been opened, and an actuator that is the thing that makes the meowing sound by playing an WAV or MP3 file), and some software. The software gets in there by hooking an in production version of the micro-controller, likely once in its life, to a regular computer via a COM port (the same kind of interface used by your mouse, or a USB connection, etc.), and stuffing the software in there.
The Arduino Uno is a micro-controller that is very generalized, very large (a bit larger than a credit card), has a well behaved power supply, lots of connectors for either sensor or actuators, and a pretty fancy brain for a micro-controller, with lots of room for code written in a very powerful and fairly easy to use language similar to objective C. You can hook the Arduino up to most computers, using freely available software to communicate with it and compile your code. For the most part, you don’t have to actually write code, it is provided by the developers of projects you are poaching, but if you want, you can go to town with it.
There are hundreds and hundreds of sensors and actuators, from thermostats to motors, gyroscopes to myriad things that light up, available for the Arduino, and in fact, anything that runs on low voltage can be hooked one way or another to it (if you know what you are doing). High voltage uses (like shifting a car or opening or closing a garage door) are done, of course, by using relays that are switches operated by a micro-controller but that pass any voltage level you want, if you get the right one.
The Arduino and its associated equipment can thus be used to replicate, design, and experiment with pretty much any thing a micro-controller can do. After “prototyping” it is trivial, for an expert, to rebuild the circuit using a less capable but perfectly adequate bunch of parts, and solder instead of just sticking things together (called “breadboarding”) and so on. But no one really does that with Arduino. With Arduino you may leave the final product at it is (like the robot we built a few weeks ago) or, as in the case of the projects in an introductory book on how to use and have fun with an Arduino, you may just take the thing you built apart and build another thing.
So, this new book, The Arduino Inventor’s Guide: Learn Electronics by Making 10 Awesome Projects, is sitting on my workbench ready to go to work.
Of all the intro Arduino books I’ve seen, this one is unique in a way I’ll explain below.
The book gives detailed, understandable, and learning-oriented instructions for a home stoplight (helpful with toddlers in the house), a reaction time garme, a balance beam game, a diminutive greenhouse, an small piano, and a handful of other projects.
The coolest project might be a living breathing Logo turtle. Logo is a computer programming environment developed years ago to serve several functions including helping kids get interesting in coding. Logo is actually one of the oldest computer languages still in use (dates to the late 60s) and it is a general programming language, but it is mainly adapted to running the Logo turtle. The turtle is a curser that is moved around on the screen, and instructed here and there to drop a specific pen (it can have several different pens) so as it moves along it draws.
This project, from The Arduino Inventor’s Guide: Learn Electronics by Making 10 Awesome Projects, is a physical turtle that draws on your rug! Or, hopefully, a big piece of drawing paper you put down for it.
I mentioned above that this book is unique. Here’s how. I’ve looked at a Lot of Audrino project books, and there are no introductory books that provide detailed information on how to make interesting project enclosures and cases. The projects in this book rely heavily on the stuff you built the electronic into. The project enclosures are generally made of simple corrugated cardboard that you can get from an old box, or, if you want, from a craft store (for more interesting colors, better quality materials, less cat hair, etc.)
You can build all the projects in this book with parts you have acquired in the usual manner, but the book suggests you get the Sparkfun Inventor’s Kit for Arduino, which is about 75 bucks. Note: This book is produced by No Starch Press and Spark Fun, so of course they suggest the Sparkfun Inventor’s Kit for Arduino
as a way of getting all the parts. But, by the time you add up an Uno or equivalent micro controller for 19 bucks
, LCD display for nine bucks
, fancy breadboard holder for 9 bucks
, a shift register for 8 bucks
, and miscellaneous other parts
, you might be over $75 anyway. Or maybe not. You’ll have to check around.
There is plenty of preliminary information to get a total novice started, and each project is rich in detail and very fully and expertly, clearly and helpfully, described.
This is an absolutely excellent choice, perhaps my favorite at the moment (and totally up to date) Arduino starter book.
Giant insects can eat tiny dinosaurs.
In this case, the giant insects are praying mantis, and the dinosaurs are hummingbirds and other small birds. In some cases, maybe most cases, this involves small birds like hummingbirds being taken at nectar sites (natural or otherwise) by introduced species of praying mantis in the US.
Here’s the info from the recently published paper:
Bird Predation By Praying Mantises: A Global Perspective, by Martin Nyffeler, Michael R. Maxwell, and J. V. Remsen, Jr.
ABSTRACT
We review 147 incidents of the capture of small birds by mantids (order Mantodea, family Mantidae). This has been documented in 13 different countries, on all continents except Antarctica. We found records of predation on birds by 12 mantid species (in the genera Coptopteryx, Hierodula, Mantis, Miomantis, Polyspilota, Sphodromantis, Stagmatoptera, Stagmomantis, and Tenodera). Small birds in the orders Apodiformes and Passeriformes, representing 24 identified species from 14 families (Acanthizidae, Acrocephalidae, Certhiidae, Estrildidae, Maluridae, Meliphagidae, Muscicapidae, Nectariniidae, Parulidae, Phylloscopidae, Scotocercidae, Trochilidae, Tyrannidae, and Vireonidae), were found as prey. Most reports (>70% of observed incidents) are from the USA, where mantids have often been seen capturing hummingbirds attracted to food sources in gardens, i.e., hummingbird feeders or hummingbird-pollinated plants. The Ruby-throated Hummingbird (Archilochus colubris) was the species most frequently reported to be captured by mantids. Captures were reported also from Canada, Central America, and South America. In Africa, Asia, Australia, and Europe, we found 29 records of small passerine birds captured by mantids. Of the birds captured, 78% were killed and eaten by the mantids, 2% succeeded in escaping on their own, and 18% were freed by humans. In North America, native and non-native mantids were engaged in bird predation. Our compilation suggests that praying mantises frequently prey on hummingbirds in gardens in North America; therefore, we suggest caution in use of large-sized mantids, particularly non-native mantids, in gardens for insect pest control.
1776 by David McCullough is not a new book — it was published in 2006 — but I just got around to reading it, enjoyed it, and wanted to say a few words about it.
But first my David McCullough story.
You probably don’t know Scotty MacNeish (aka Richard Stockton MacNeish), but you should. He ended his illustrious career in a car accident in the field (in Belize, if I recall correctly) about 15 years ago, but many years before that he started out his career by discovering the origin of Continue reading 1776: A man, his war, and their year
At the moment, all these are anywhere from free to two bucks. The Darwin books are always cheap, the others are probably temporarily cheap.
If you’ve not read The Autobiography of Charles Darwin, you should. It is always avaialable for next to nothing on the kindle, currently this version is 99 cents.
Concerning his autobiography–written when Darwin was 59 and originally published as the first part of “The Life and Letters of Charles Darwin” (1887)–Darwin explained: “A German editor [wrote] to me for an account of the development of my mind and character with some sketch of my autobiography. I have thought that the attempt would amuse me, and might possibly interest my children or their children. I have attempted to write the following account of myself as if I were a dead man in another world looking back at my own life. Nor have I found this difficult, for life is nearly over with me. I have taken no pains about my style of writing.”
Darwin’s son Francis, who edited “Life and Letters,” stated: “My father’s autobiographical recollections were written for his children—and written without any thought that they would ever be published. To many this may seem an impossibility; but those who knew my father will understand how it was not only possible, but natural.”
The autobiography was reprinted in 1908 as a section of editor George Iles’ larger “Little Masterpieces of Autobiography: Men of Science.” This Kindle edition, equivalent to a physical book of approximately 24 pages, includes the complete text of that 1908 reprint.
(You can get The Origin of Species by Means of Natural Selection for free or a buck as well.)
Jared Diamond’s The World Until Yesterday: What Can We Learn from Traditional Societies? is currently cheap, $1.99 in Kindle form.
Most of us take for granted the features of our modern society, from air travel and telecommunications to literacy and obesity. Yet for nearly all of its six million years of existence, human society had none of these things. While the gulf that divides us from our primitive ancestors may seem unbridgeably wide, we can glimpse much of our former lifestyle in those largely traditional societies still or recently in existence. Societies like those of the New Guinea Highlanders remind us that it was only yesterday—in evolutionary time—when everything changed and that we moderns still possess bodies and social practices often better adapted to traditional than to modern conditions.The World Until Yesterday provides a mesmerizing firsthand picture of the human past as it had been for millions of years—a past that has mostly vanished—and considers what the differences between that past and our present mean for our lives today.
This is Jared Diamond’s most personal book to date, as he draws extensively from his decades of field work in the Pacific islands, as well as evidence from Inuit, Amazonian Indians, Kalahari San people, and others. Diamond doesn’t romanticize traditional societies—after all, we are shocked by some of their practices—but he finds that their solutions to universal human problems such as child rearing, elder care, dispute resolution, risk, and physical fitness have much to teach us. Provocative, enlightening, and entertaining, The World Until Yesterday is an essential and fascinating read.
I’ve not read this but it looks really interesting and cheap at twice the price: Close to Shore: The Terrifying Shark Attacks of 1916
Combining rich historical detail and a harrowing, pulse-pounding narrative, Close to Shore brilliantly re-creates the summer of 1916, when a rogue Great White shark attacked swimmers along the New Jersey shore, triggering mass hysteria and launching the most extensive shark hunt in history.
In July 1916 a lone Great White left its usual deep-ocean habitat and headed in the direction of the New Jersey shoreline. There, near the towns of Beach Haven and Spring Lake–and, incredibly, a farming community eleven miles inland–the most ferocious and unpredictable of predators began a deadly rampage: the first shark attacks on swimmers in U.S. history.
Capuzzo interweaves a vivid portrait of the era and meticulously drawn characters with chilling accounts of the shark’s five attacks and the frenzied hunt that ensued. From the unnerving inevitability of the first attack on the esteemed son of a prosperous Philadelphia physician to the spine-tingling moment when a farm boy swimming in Matawan Creek feels the sandpaper-like skin of the passing shark, Close to Shore is an undeniably gripping saga.
Heightening the drama are stories of the resulting panic in the citizenry, press and politicians, and of colorful personalities such as Herman Oelrichs, a flamboyant millionaire who made a bet that a shark was no match for a man (and set out to prove it); Museum of Natural History ichthyologist John Treadwell Nichols, faced with the challenge of stopping a mythic sea creature about which little was known; and, most memorable, the rogue Great White itself moving through a world that couldn’t conceive of either its destructive power or its moral right to destroy.
Scrupulously researched and superbly written, Close to Shore brings to life a breathtaking, pivotal moment in American history. Masterfully written and suffused with fascinating period detail and insights into the science and behavior of sharks, Close to Shore recounts a breathtaking, pivotal moment in American history with startling immediacy.
Genius in the Shadows: A Biography of Leo Szilard, the Man Behind the Bomb by by William Lanouette looks interesting:
Well-known names such as Albert Einstein, Enrico Fermi, J. Robert Oppenheimer, and Edward Teller are usually those that surround the creation of the atom bomb. One name that is rarely mentioned is Leo Szilard, known in scientific circles as “father of the atom bomb.” The man who first developed the idea of harnessing energy from nuclear chain reactions, he is curiously buried with barely a trace in the history of this well-known and controversial topic.
Born in Hungary and educated in Berlin, he escaped Hitler’s Germany in 1933 and that first year developed his concept of nuclear chain reactions. In order to prevent Nazi scientists from stealing his ideas, he kept his theories secret, until he and Albert Einstein pressed the US government to research atomic reactions and designed the first nuclear reactor. Though he started his career out lobbying for civilian control of atomic energy, he concluded it with founding, in 1962, the first political action committee for arms control, the Council for a Livable World.Besides his career in atomic energy, he also studied biology and sparked ideas that won others the Nobel Prize. The Salk Institute for Biological Studies in La Jolla, California, where Szilard spent his final days, was developed from his concepts to blend science and social issues.
You’ve seen this horrid person in this horrid video calling for white people to take up arms and kill black people (and maybe Jews).

But anyone with 2+ neurons to rub together and who has not been living in a cave for the last 30 years knows the exact meaning of “clenched fist” and “I’m freedom’s safest place [gasp]” against the propaganda spread by the (here’s the part about the Jews) entertainment industry about how “them,” “them,” “them,” and “them” (insert visuals of uppity black people).
I’m not going to link to that appalling ad. But it has been described as
a … propaganda video disguised as a recruitment ad that takes aim at the Black Lives Matter movement and uses lies in order to whip its supporters into a frenzy and encourage them to take up arms to protect themselves from a supposed enemy.
As activist Deray McKesson notes, “If I made a video like this, I’d be in jail.”
Black Lives Matter Los Angeles, Dignity and Power Now, The Reverence Project, RISIST, and Defend Movement produced the following powerful and true video in response to the NRA’s call to White Supremacy.
Don’t just watch part of it, watch the whole thing. It has a structure you do not want to miss.
It starts with a very simple question: Is global warming real and human caused? It ends with a very simple answer: Yes to both. But in the middle we have, like every other good story, sex, intrigue, and intriguing sex.
In the beginning, there was a strong theory that said, “If we add greenhouse gasses, such as CO2, the byproduct of burning fossil fuels, to the atmosphere, the planet will warm.” But direct observations of this warming actually happening were sketchy. Widespread systematically collected and curated temperature records only went back a few decades, and as we were to learn later, the warming that was indeed happening was undergoing a quiescence. Such slower periods are interspersed with periods of rapid warming as part of the natural variation in the Earth’s climate system. In short, there is a natural component to variation in the Earth’s surface temperature, and a human-caused component, and at the time the human component was not yet the dominating force it would soon become.
Eventually, the record of surface temperatures was pushed back decade by decade through the diligent collection, critical evaluation, and cleaning up of data that had been sitting around in hand written form in myriad locations. The direct measurements of surface temperatures was extended back over a century, and at the same time, because that took a while, a decade or two of actual time passed by, during which thermometer and satellite data were collected. Now, we can look back to 1850 or 1880 (depending on the database) up to the present, and we see a warming trend.
A lot of research was being done those days, in the 1970s and 1980s, in paleoclimate and climatology. In particular, proxyindicators were being developed and contributing significant data. I remember as a young pre-graduate student sitting in a class where the professor was carefully explaining what a “proxy” was, as though no one had ever heard of them before (and we hadn’t). A proxy is a signal obtained from some natural material such as glacial ice, the sediment at the bottom of a pond or an ocean, or the pattern of growth rings of trees. This signal is linked via a model of some sort to a desired measurement (such as sea level, or temperature, or something) to imitate an instrument over the time covered by the proxy.
Just two years later, I remember an impromptu conference organized by my advisor, with a half dozen of the key paleoclimatologists, in which they provided updates to current research coming out of oceanography, and it was pretty amazing. Suddenly, using ocean cores, Oxygen isotopes, and theory, it was possible to make a reliable and remarkably precise estimate of how much water was missing from the ocean at any given time. Since most of that missing water was trapped in glacial ice, this proxy became the first accurate tracking of the comings and goings, and patterns of, Pleistocene ice ages. At first the record only went back 500,000 years. Then 800,00 years. Now, it is being extended back further.
Roughly ten years or so later, by the time 1998 rolled around, the world of climate science was ready for one of those pivotal moments to come along, and it did. This was the publication by Michael E. Mann, Raymond S. Bradley, Malcolm K. Hughes, of research linking long term records of the Earth’s surface temperature with more recent data, showing a clear signal of recent human-caused warming. Subsequently, that result, sometimes referred to as the “Hockey Stick Graph” because it looks somewhat like a hockey stick, has been confirmed over and over again. The best place to get a review of that research and its subsequent verification is in a post by climate scientist Stefan Rahmstorf called “Most Comprehensive Paleoclimate Reconstruction Confirms Hockey Stick.”
(Added: See also the reference to Jones et al in this blog post pertaining to the history of all of this, by John Mashey.)
There have always been science deniers. God was a denier (“…you must not eat from the tree of the knowledge…”). Galileo was harassed by deniers. I recently read a quote from a late 18th century, of a British soldier, referring with derision to the “bible-faced Americans” and, certainly, the American Christian churches have found anti-science activism and rhetoric to be excellent, um, fertilizer, to enhance their own growth.
The deniers of climate change didn’t just get the gas for their cars from Big Oil; Their entire movement was, and is, fueled by the likes of the Koch Brothers, deep pocketed one percenters and corporations harboring the unfortunate delusion that if we pretend climate change is not caused by the burning of fossil fuels, everything will be fine and they’ll keep getting rich.
The publication of the Hockey Stick research became a focusing point for these deniers, and Michael Man, the lead on that research, became a target on which they have fired continuously since then. No living scientist, no recent deceased scientists, and perhaps no scientist in history, has experienced such a sustained violation by so many deniers over such a period of time as Mike Mann. You can read all about the first phase of this relentless attack in this book by Mann himself.
You can disagree with a scientist. In fact, please do. Maybe the scientist is wrong about something. Chances are, if you are not a scientist and your disagreement is about something the scientist is an expert on and you are not, there is a different problem. Perhaps the science has not been explained clearly, and that is a problem, a reasonable thing to ask about. That can also be fixed. If, however, the science has been explained, and you maintain your disagreement not because the scientist is wrong, but because you want the scientist to be wrong, or because it is in your financial or political interest to disagree or cause confusion or sow doubt then … well, you can still do that because this is a free country.
In America, you can be an asshole.
But, if you publicly claim of anyone, in this country, that they have committed a crime, and they didn’t, especially if you make this claim with nefarious intent, then it is you who have potentially committed an offense, perhaps a civil offense, perhaps libel. In Canada they have similar rules. Lots of countries have that rule.
As the number one target of climate deniers world wide and for decades, Michael Mann has been defamed a number of times. On a couple of those occasions, with the support of various groups, Mann has pursued his legal and ethical right to fight back, and has filed suit.
I know Michael Mann well enough to know that this is not libel tourism. This is not Mann trying to make a fast buck. Mann would probably be fine in each case if the defendants had simply withdrawn the libel. (Given the nature of court costs and such, and the tenacious and obnoxious nature of the defense pretty much universally as I’ve seen it, I have no idea what the status of possible settlement is at this time and I’m sure everyone involved is under legal recommendation to not speak of such things at this time.)
One of these cases is against Tim Ball. Who is Tim Ball?
Ball has a PhD from the University of London (1982). According to the DeSmogBlog database on climate deniers,
Tim Ball was a professor of geography at the University of Winnipeg from 1988 to 1996. He is a prolific speaker and writer in the skeptical science community.
He has been Chairman to the now-defunct Natural Resources Stewardship Project (NRSP), “Consultant” to the Exxon-funded Friends of Science (FoS), senior fellow at the Frontier Centre for Public Policy (FCPP), and has connections to numerous other think tanks and right-wing organizations.
Tim Ball is member of Climate Exit (Clexit), a climate change denial group formed shortly after the UK’s decision to leave the EU. According to Clexit’s founding statement (PDF), “The world must abandon this suicidal Global Warming crusade. Man does not and cannot control the climate.”
…
Ball and the organizations he is affiliated with have repeatedly made the claim that he is the “first Canadian PhD in climatology.” Ball himself claimed he was “one of the first climatology PhD’s in the world.”
Many have pointed out that there have been numerous PhD’s in the field prior to Ball.
Ball was a former professor of geography at the University of Winnipeg from 1988 to 1996. The University of Winnipeg never had an office of Climatology. His degree was in historical geography and not climatology. [12]
…
A search of 22,000 academic journals shows that over the course of his career Ball published four pieces of original research in peer-reviewed journals on the subject of climate change.
According to Google Scholar, his most recent peer-reviewed article on climate change was published in 1986, titled “Historical evidence and climatic implications of a shift in the boreal forest tundra transition in central Canada.”
…
Tim Ball is a prolific writer of newspaper articles, opinion pieces, and letters to the editor questioning the existence of climate change. [51]Ball is also a lead author of Slaying the Sky Dragon: Death of the Greenhouse Gas Theory, a book published in 2011.
In 2011, Michael Mann filed suit against Ball and a Canadian think tank for claiming that Mann carried out criminal fraud. The nature of the fraud claim is a little complex and muddled, but it was part of the ongoing attack on Mann discussed in the above mentioned book. Ultimately this has to do with a bunch of innocuous private emails that had been exchanged among colleagues, then stolen by nefarious actors, cherry picked to make it look like bad things had happened, and widely publicized. In relation to this alt-news now known as “climategate” Ball said, “Michael Mann at Penn State should be in the State Pen, not Penn State.”
This is not the only law suit against Tim Ball. He has made similar accusations against others as well.
Now, that is all very interesting. But here is where it starts to get strange.
I am happy to have a wide range of commenters on my blog, and I trust my regular readers to handle those with racist, sexist, or anti-science tendencies. But I was a little shocked the other day to get a comment by someone I had never heard of before, ranting about Michael Mann and making claims about the Mann vs. Ball lawsuit that I knew were false.
The commenter used the name “Starchild.” I’d heard of Starchild, but I was suspicious that an alien hoax was commenting on my blog. So, I contacted this Starchild chap and asked if he was for real. Turns out, his real life name is none other than Starchild, and he is a famous San Francisco based bi-sexual sex worker Libertarian. Like this:
Starchild, in his comments, was essentially parroting a guy named John O’Sullivan. O’Sullivan runs a really nasty anti-science blog, and is well known for a wide range of shenanigans.
Sullivan was making legal claims about the Mann vs. Ball law suit, and I’ll get to that in a moment. But first, who is John O’Sullivan?
Sometimes John O’Sullivan claims to be a lawyer, but sometimes he backs off that claim.
According to himself, John O’Sullivan is not lawyer, but “… just some Brit with a brain who can go live with his American wife in her country and kick ass big time around a courtroom.”
He is the author of “Vanilla Girl: a Fact-Based Crime Story of a Teacher’s Struggle to Control His Erotic Obsession with a Schoolgirl.” This is an online book of some kind (I looked, it is not on Amazon).
O’Sullivan was successful in winning an acquittal when he was personally charged in England as a high school teacher accused of sending lewd text messages and assaulting a 16-year-old female. Given the acquittal, it would not generally be appropriate to bring up this sordid and unproven bit of history, except that O’Sullivan himself went on to write an “erotic” “novel” with a startlingly similar storyline: Vanilla Girl: a Fact-Based Crime Story of a Teacher’s Struggle to Control His Erotic Obsession with a Schoolgirl.
[source]
O’Sullivan claimed that he was an experienced attorney with an excellent record in New York and US federal courts. He isn’t. He identified a major law firm that he worked for. He didn’t work for them. He claims a fairly imporessive writing resume including some major outlets such as Forbes. None of that was true. He claims to be a member of the American Bar association but isn’t. He may or may not have a fake law degree from an on line alt-degree mill.
To focus this line of thoughtlessness on the issue at hand, I’ll replicate Starchild’s comments here (combined into one):
Now that Michael Mann is in danger of being held in contempt of court for failing to release his research data, who’s the climate science “denier”? Hmm…
In his blog entry at http://scienceblogs.com/gregladen/2014/08/15/electronic-frontier-foundation-messes-up/ , Greg Laden wrote, “I’ll add that Mann’s research is all open source or open access with respect to data, methods, software, and results.”
It is, is it? Maybe that’s what he wanted you to think, until the time came when he actually had to produce:
“Prominent alarmist shockingly defies judge and refuses to surrender data for open court examination…
“(Climatologist Dr. Tim) Ball explains, ‘We believe he [Mann] withheld on the basis of a US court ruling that it was all his intellectual property. This ruling was made despite the fact the US taxpayer paid for the research and the research results were used as the basis of literally earth-shattering policies on energy and environment. The problem for him is that the Canadian court holds that you cannot withhold documents that are central to your charge of defamation regardless of the US ruling.’”
Let’s begin right away with the data that is supposedly being held secret. They are HERE They have always been there. Anytime anyone says “where’s the data, Michael Mann” just send them there, where the data are.
Regarding the rest of O’Sullivan’s claims as echoed by Starchild, this is a statement by Michael Mann’s attorney:
Contrary to the nonsensical allegations made by John O’Sullivan in his July 4 posted on climatechangedispatch.com and elsewhere, plaintiff Michael Mann has fully complied with all of his disclosure obligations to the defendant Tim Ball relating to data and other documents.
No judge has made any order or given any direction, however minor or inconsequential, that Michael Mann surrender any data or any documents to Tim Ball for any purpose.
Accordingly it should be plain and obvious to anyone with a modicum of common sense that Mann could not possibly be in contempt of court.
Just to be clear: Mann is not defying any judge. He is not in breach of any judgment. He is not, repeat not, in contempt of court. He is not in breach of any discovery obligations to Ball.
In this context, O’Sullivan’s suggestion that Ball “is expected to instruct his British Columbia attorneys to trigger mandatory punitive court sanctions” against Mann is simply divorced from reality.
Finally, a word about the actual issues in the British Columbia lawsuit.
If O’Sullivan had read Ball’s statement of defence, he would immediately see that Ball does not intend to ask the BC Court to rule that Mann committed climate data fraud, or that Mann in fact did anything with criminal intent.
O’Sullivan would have noticed that one of Ball’s defences is that the words he spoke about Mann (which are the subject of Mann’s lawsuit) were said in “jest.”The BC Court will not be asked to decide whether or not climate change is real.
So there is no chance whatsoever that any BC Court verdict about Mann’s libel claims against Ball will vindicate Donald Trump’s perspective on climate change.Roger D. McConchie
Also, the data are here.
People talk about resurrecting the Mammoth, the Dodo, the Quagga, or the Tasmanian devil, or any number of extinct (or mostly extinct) creatures. I’m all for that. I suggest removing cattle farming in Nebraska, Wyoming, Montana and adjoining areas of Canada, and repopulating the region with extinct megafauna. That would just be cool.
There are difficulties with this, including figuring out exactly how to piece together the genome for the extinct animal, how to get a good level of genetic diversity in the neo-founding population, and how to raise the critter up from a zygote. For all these reasons, I’ve always thought we should start by resurrecting something that already exists. We normally do this sort of dry run or practice run with things we do. In baseball, golf, and other ball sports, athletes take pre-swings. We went “to” the moon a couple of times before landing “on” the moon. Etc. So, let’s start by resurrecting a fruit fly, them maybe a chicken, then a dog. That sort of thing.
A potentially important public health concern is the re-emergence, one way or another, of small pox or something like small pox. In order to manage that, we would like to see more research involving vaccines. An ideal way to carry out vaccine research without risking the release of full blown small pox (which may or may not be frozen somewhere) on the population is to create a small pox virus (small pox is a virus) from scratch, using a known genetic code. In so doing, the parts of the virus that allow it to spread could be denatured, and the parts of the virus that allow research for vaccines or cures could be left in place.
In essence, creating such a Frankensteinian life form is like resurrecting an extinct species. And, some Canadian scientists stole my idea and went ahead and resurrected a non-extinct species in order to test out the plausibility of the method. The research is not published and likely won’t be, because it would be too easily misused by nefarious actors. But, the results were discussed at a meeting several months ago, and now there is something new about it in Science:
Eradicating smallpox, one of the deadliest diseases in history, took humanity decades and cost billions of dollars. Bringing the scourge back would probably take a small scientific team with little specialized knowledge half a year and cost about $100,000.
That’s one conclusion from an unusual and as-yet unpublished experiment performed last year by Canadian researchers. A group led by virologist David Evans of the University of Alberta in Edmonton, Canada, says it has synthesized the horsepox virus, a relative of smallpox, from genetic pieces ordered in the mail. …
The story is also covered by the Washington Post.
And, here is a previously released press release:
Tonix Pharmaceuticals Announces Demonstrated Vaccine Activity in First-Ever Synthesized Chimeric Horsepox Virus
Pre-Clinical Smallpox-Preventing Vaccine Candidate TNX-801 May Qualify for Priority Review Voucher if FDA-Approved Under Provisions in the 21st Century Cures Act
NEW YORK, March 02, 2017 (GLOBE NEWSWIRE) — Tonix Pharmaceuticals Holding Corp. (Nasdaq:TNXP) (Tonix), a company that is developing innovative pharmaceutical products to address public health challenges, working with researchers from the University of Alberta, a leading Canadian research university, today announced the successful synthesis of a potential smallpox-preventing vaccine. This vaccine candidate, TNX-801, is a live form of horsepox virus (HPXV) that has been demonstrated to have protective vaccine activity in mice.
“Presently, the safety concern of existing smallpox-preventing vaccines outweigh the potential benefit to provide immunization of first responders or the general public. By developing TNX-801 as a horsepox vaccine to prevent smallpox infection, we hope to have a safer vaccine to protect against smallpox than is currently available,” stated Seth Lederman, M.D., president and chief executive officer of Tonix. “Vaccines are a critical component of the infrastructure of global public health. Vaccination protects those who are vaccinated and also those who are not vaccinated, by decreasing the risk of contagion.”
“Our goal is to improve on current methods that protect the public from possible viral outbreaks,” said Professor David Evans, Ph.D., FCAHS, Professor and Vice-Dean (Research), Faculty of Medicine and Dentistry at the University of Alberta, in Edmonton, Alberta, Canada, and principal investigator of the TNX-801 research project.
HPXV was synthesized by Professor Evans and Research Associate Ryan Noyce, Ph.D., at the University of Alberta, with Dr. Lederman as co-investigator of the research and co-inventor of the TNX-801 patent. Under their research and development agreement, Tonix wholly owns the synthesized HPXV virus stock and related sequences. Professor Evans and Dr. Noyce also demonstrated that HPXV has protective vaccine activity in mice, using a model of lethal vaccinia infection. Vaccine manufacturing activities have been initiated by Tonix to support further nonclinical testing of TNX-801.
Dr. Lederman stated, “Our research collaboration is dedicated to creating tools and innovative products that better protect public health.”
About Horsepox (HPXV) and Smallpox
Horsepox, an equine disease caused by a virus and characterized by eruptions in the mouth and on the skin, is believed to be eradicated. No true HPXV outbreaks have been reported since 1976, at which time the United States Department of Agriculture obtained the viral sample used for the sequence published in 2006 that allowed the synthesis of TNX-801. In 1798, Dr. Edward Jenner, English physician and scientist, speculated that smallpox is a human version of pox diseases in animals. Jenner had a strong suspicion that his vaccine began as a pox disease in horses and went on to show that it could be used to vaccinate against smallpox. Smallpox was eradicated as a result, and no cases of naturally occurring smallpox have been reported since 1977. Jenner’s vaccine appears to have evolved considerably in the vaccinia stocks maintained in different countries around the world, since vaccinia was mostly selected for growth and production. Being able to provide safe and effective smallpox-preventing vaccines remains important and necessary for addressing and protecting public health.
About the Material Threat Medical Countermeasures Provisions in the 21st Century Cures Act
In 2016, the 21st Century Cures Act (Act) was signed into law to support ongoing biomedical innovation. One part of the Act, Section 3086, is aimed at “Encouraging Treatments for Agents that Present a National Security Threat.” This section of the Act created a new priority review voucher program for “material threat medical countermeasures.” The Act defines such countermeasures as drugs or vaccines intended to treat biological, chemical, radiological, or nuclear agents that present a national security threat, or to treat harm from a condition that may be caused by administering a drug or biological product against such an agent. The priority review vouchers are awarded at the time of FDA approval and are fully transferrable and may be sold to other companies to be used for priority review of any New Drug Application (NDA) or Biologic Licensing Application (BLA).
About Tonix Pharmaceuticals Holding Corp.
Tonix is developing innovative pharmaceutical products to address public health challenges, with TNX-102 SL in Phase 3 development for posttraumatic stress disorder (PTSD). TNX-102 SL is designed for bedtime use and is believed to improve overall PTSD symptoms by improving sleep quality in PTSD patients. PTSD is a serious condition characterized by chronic disability, inadequate treatment options especially for military-related PTSD and overall high utilization of healthcare services creating significant economic burden. TNX-102 SL was recently granted Breakthrough Therapy designation by the FDA for the treatment of PTSD. Other development efforts include TNX-601, a clinical candidate at Pre-IND (Investigational New Drug) application stage, designed for daytime use for the treatment of PTSD, and TNX-801, a potential smallpox-preventing vaccine.
*TNX-102 SL (cyclobenzaprine HCl sublingual tablets) is an investigational new drug and has not been approved for any indication.
This press release and further information about Tonix can be found at www.tonixpharma.com.
Forward Looking Statements
Certain statements in this press release are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995. These statements may be identified by the use of forward-looking words such as “anticipate,” “believe,” “forecast,” “estimate,” “expect,” and “intend,” among others. These forward-looking statements are based on Tonix’s current expectations and actual results could differ materially. There are a number of factors that could cause actual events to differ materially from those indicated by such forward-looking statements. These factors include, but are not limited to, substantial competition; our need for additional financing; uncertainties of patent protection and litigation; uncertainties of government or third party payor reimbursement; limited research and development efforts and dependence upon third parties; and risks related to failure to obtain FDA clearances or approvals and noncompliance with FDA regulations. As with any pharmaceutical under development, there are significant risks in the development, regulatory approval and commercialization of new products. Tonix does not undertake an obligation to update or revise any forward-looking statement. Investors should read the risk factors set forth in the Annual Report on Form 10-K for the year ended December 31, 2015, as filed with the Securities and Exchange Commission (the “SEC”) on March 3, 2016, and future periodic reports filed with the SEC on or after the date hereof. All of Tonix’s forward-looking statements are expressly qualified by all such risk factors and other cautionary statements. The information set forth herein speaks only as of the date hereof.