Tag Archives: River Blindness

More on river blindness and related diseases

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We were talking about River Blindness.

Trigger Warning: The video below is not for general consumption. Having said that you may want to watch it. The first part depicts the reactions of a handful of celebrities watching a series of shots depicting seven different related tropical diseases, and I must say, having seen all of these diseases in person (and having treated some of them, and had mild versions of a couple myself) that these particular videos show the worst side of it. But still, a very large number of people (according to the source of the video, about a billion) have some form of these diseases, mainly in Africa but also in Central and South America and Asia. The celebrities are: Emily Blunt (“Salmon Fishing in the Yemen,” “Devil Wears Prada”); Eddie Redmayne (“Les Miserables,” “My Week with Marilyn”); Tom Felton (“Harry Potter” series); Yvonne Chaka Chaka (South African pop star); Tom Hollander (“Pirates of the Caribbean,” “Pride and Prejudice”); and Priyanka Chopra (leading Bollywood actress and international recording artist).

The last part of the video is the same celebs giving a pitch for you to pitch in and donate some money and spread some awareness.

The project that produced this video is called End7, a reference to ending all seven diseases. What they say is mostly true: You can treat these diseases very inexpensively. At present, the pharmaceuticals are well known and inexpensive. However, people with advanced stages of some of these parasitic infections can’t be treated easily if at all because the treatment may involve causing effects that result in very severe immune system responses. The idea is to treat children, more or less prophylactically, so they don’t develop the advanced versions.

The disease are:

<ul>
  • Elephantiasis
    • <li>Roundworm</li>

<li>Hookworm</li>

<li>Whipworm</li>

<li>Trachoma</li>

<li>River Blindness</li>

<li>Snail Fever</li></ul>

    A Test For River Blindness

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    River blindness, also called Onchocerciasis, is the result of the infection of several different eye tissues by the nematode Onchocerca volvulus. The bacterium Wolbachia pipientis lives symbiotically in the gut of the nematode, and escapes the small roundworm to cause an inflammatory response in human tissues, which results in damage to the tissue. These infections can occur in a number of different human tissues causing a variety of effects, but when the eye tissues are involved, the result can be river blindness. It is endemic and widespread in several areas of Africa, as well as more restricted areas in South America and the Middle East.

    ResearchBlogging.orgTreatment of the disease involves killing the bacterium, which in turn kills the host nematode, using various anti-biotics. However, as we have learned over recent decades, widespread use of antibiotics can be less than ideal because this can cause selection for resistant strains so that treatment can become generally ineffective across an affected population. Ideally, there would be a reliable test for river blindness infection that would allow more targeted use of treatments. Continue reading A Test For River Blindness →