Daily Archives: February 8, 2011

A Universal, One-Shot Flu Vaccine?

ResearchBlogging.orgA Better Grip: T Cells Strengthen Our Hand against Influenza Clinical Infectious Diseases, 52 (1), 8-9 DOI: 10.1093/cid/ciq018Flu vaccines are important and useful, but also relatively ineffective compared to many other vaccines. Immunity is imperfect, there are many ‘strains’ of influenza in a given year only some of which are addressed by the available vaccine (though often the most common ones) and one year’s vaccine does not provide immunity to subsequent years’ influenza because the virus changes so much. Well, actually that’s not exactly true: The influenza virus has various different parts, and the parts that the traditional flu vaccine uses to induce an antigenic reaction in the potential hose is highly variable. Other parts of the flu virus are not as variable. If only a vaccine could be developed that uses the less variable part of the influenza virus, then perhaps it would be a universal, long-lasting vaccine that you take once, and become pretty much immune to all future influenza.
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