{"id":577,"date":"2007-12-11T22:48:53","date_gmt":"2007-12-11T22:48:53","guid":{"rendered":"http:\/\/scienceblogs.com\/gregladen\/2007\/12\/11\/reprogramming-adult-cells-to-c\/"},"modified":"2007-12-11T22:48:53","modified_gmt":"2007-12-11T22:48:53","slug":"reprogramming-adult-cells-to-c","status":"publish","type":"post","link":"https:\/\/gregladen.com\/blog\/2007\/12\/11\/reprogramming-adult-cells-to-c\/","title":{"rendered":"Reprogramming Adult Cells to Cure Sickle-Cell"},"content":{"rendered":"<blockquote><p>MIT researchers have successfully treated mice with sickle-cell anemia in a process that begins by directly reprogramming the mice&#8217;s own cells to an embryonic-stem-cell-like state, without the use of eggs.This is the first proof-of-principle of therapeutic application in mice of directly reprogrammed induced pluripotent stem (IPS) cells, which recently have been derived in mice as well as humans.&#8221;This demonstrates that IPS cells have the same potential for therapy as embryonic stem cells, without the ethical and practical issues raised in creating embryonic stem cells,&#8221; said MIT biology professor Rudolf Jaenisch, a member of the Whitehead Institute for Biomedical Research.<a href=\"http:\/\/web.mit.edu\/newsoffice\/2007\/sickle-cell-1207.html\">[Source]<\/a><\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>MIT researchers have successfully treated mice with sickle-cell anemia in a process that begins by directly reprogramming the mice&#8217;s own cells to an embryonic-stem-cell-like state, without the use of eggs.This is the first proof-of-principle of therapeutic application in mice of directly reprogrammed induced pluripotent stem (IPS) cells, which recently have been derived in mice as &hellip; <a href=\"https:\/\/gregladen.com\/blog\/2007\/12\/11\/reprogramming-adult-cells-to-c\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Reprogramming Adult Cells to Cure Sickle-Cell<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"1","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[103],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p5fhV1-9j","jetpack_likes_enabled":true,"_links":{"self":[{"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/posts\/577"}],"collection":[{"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/comments?post=577"}],"version-history":[{"count":0,"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/posts\/577\/revisions"}],"wp:attachment":[{"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/media?parent=577"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/categories?post=577"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/tags?post=577"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}