{"id":10019,"date":"2011-07-30T11:49:16","date_gmt":"2011-07-30T11:49:16","guid":{"rendered":"http:\/\/scienceblogs.com\/gregladen\/2011\/07\/30\/we-can-know-nothing-about-the\/"},"modified":"2011-07-30T11:49:16","modified_gmt":"2011-07-30T11:49:16","slug":"we-can-know-nothing-about-the","status":"publish","type":"post","link":"https:\/\/gregladen.com\/blog\/2011\/07\/30\/we-can-know-nothing-about-the\/","title":{"rendered":"&#8220;We can know nothing about the origin of life&#8221;"},"content":{"rendered":"<p><strong><em>Falsehood!!! <\/em><\/strong><\/p>\n<p>Sometimes people say this because it seems reasonable to them &#8230; what, with life originating so long ago and so much geological mushing-around happening since then. But sometimes people say this, and sound quite innocent saying it, because they want to throw the average person off track and make them think that Evolutionary Biology has this big gap &#8212; at the beginning &#8212; in which any-old kind of story can fit, including a supernatural or religious story, or even just a spiritual Jungian story, or anything but a story about molecules interacting.<\/p>\n<p>So, the purpose of this blog post is to be handy, to point to, to produce a link to, in answer to that question.  Every time somebody says &#8220;We can know nothing about the origin of life bla bla bla&#8221; you respond with a link to this post.  In the meantime, if you think there is something missing in this post that should be conveyed to anyone making that argument, please add it to the comments.<\/p>\n<p>Here&#8217;s the code to copy and past to link to this post:<\/p>\n<p>&lt;a href=&#8221;http:\/\/scienceblogs.com\/gregladen\/2011\/07\/we_can_know_nothing_about_the.php&#8221;>&#8221;We can know nothing about the origin of life&#8221;&lt;\/a><\/p>\n<p>Below are two lists. The first list is a set of blog posts by a variety of science bloggers about the origin of life.  The second list is the bibliography my installation of <a href=\"http:\/\/www.mendeley.com\/\">Mendeley<\/a> (reference management software) spit out at me when I asked it to find all the references to &#8220;Origin of Life&#8221; on my hard drive or nearby localities. This includes only a subset (about 5%) of my PDF files and none of my paper files (of which there are about 5,000) of which, in turn, probably only 1 or 2% address this issue, as it is not my field.<\/p>\n<p>So, the reference list is provisional and just to get your stared, but also serves the purpose of demonstrating how there is quite a bit of work on the topic.<\/p>\n<p>At present, we know something about the origin of life. I think we could know a lot more, and I think we will eventually.  The assertion that we can&#8217;t because it isn&#8217;t happening now and happened a long time ago is wrong for several reasons:  1) Are you sure it is not happening now?; 2) It could be replicated in the lab; 3) It might be happening somewhere else, or evidence of it could be found on another celestial object; and 4) Yes, indeed, it turns out that we actually can reconstruct things through inference from ancient data, modeling, and experiment that happened in the past, and do so scientifically.  If you hear someone telling you that you can&#8217;t, that this is not science, that it violates the scientific method, then you are hearing the words of a person who either knows nothing about science or is telling you a lie, because science can and does address the past.<\/p>\n<p>So, without further ado, the lists:<\/p>\n<p><!--more--><br \/>\n<em><strong>A sampling of blog posts on the origin of life:<\/strong><\/em><\/p>\n<p><a href=\"http:\/\/scienceblogs.com\/gregladen\/2011\/06\/is_the_origin_of_life_differen.php\">Is the origin of life different from evolution?<\/a><br \/>\n<a href=\"http:\/\/blogs.nature.com\/from_the_lab_bench\/2011\/07\/26\/super-hero-experiment-1-the-origin-of-life\">Super-Hero Experiment #1: The Origin of Life<\/a><br \/>\n<a href=\"http:\/\/bioteaching.wordpress.com\/2011\/05\/27\/the-origin-of-life-and-of-the-atmosphere\/\">The Origin of Life and of the Atmosphere<\/a><br \/>\n<a href=\"http:\/\/ogremk5.wordpress.com\/2011\/03\/18\/origins-of-life-%E2%80%93-amino-acids-and-the-triplet-codon\/\">Origins of Life &#8211; Amino Acids and the Triplet Codon<\/a><br \/>\n<a href=\"http:\/\/ogremk5.wordpress.com\/2011\/03\/11\/origin-of-life-rna-self-replicators\/\">Origin of Life &#8211; RNA Self Replicators<\/a><br \/>\n<a href=\"http:\/\/wavefunction.fieldofscience.com\/2010\/12\/new-place-new-view-slow-reactions-and.html?utm_source=feedburner&#038;utm_medium=feed&#038;utm_campaign=Feed%3A+curiouswavefunction+%28The+Curious+Wavefunction%29\">New place, new view, slow reactions and the origins of life<\/a><br \/>\n<a href=\"http:\/\/scienceblogs.com\/gregladen\/2010\/12\/nasas_new_organism_the_meaning.php\">NASA&#8217;s new organism, the meaning of life, and Darwin&#8217;s Second Theory<\/a><br \/>\n<a href=\"http:\/\/leafwarbler.posterous.com\/arsenic-and-old-lace\">Arsenic and Old Lace<\/a><br \/>\n<a href=\"http:\/\/blogs.openaccesscentral.com\/blogs\/bmcblog\/entry\/common_ancestry_of_life_q\">Common ancestry of life &#8211; Q.E.D?<\/a><br \/>\n<a href=\"http:\/\/pleiotropy.fieldofscience.com\/2010\/08\/report-from-alife-xii-lifes-origin-and.html\">Report from Alife XII: life&#8217;s origin, and its evolution<\/a><br \/>\n<a href=\"http:\/\/wavefunction.fieldofscience.com\/2010\/06\/origin-of-life-cannot-escape-basic.html?utm_source=feedburner&#038;utm_medium=feed&#038;utm_campaign=Feed%3A+curiouswavefunction+%28The+Curious+Wavefunction%29\">The origin of life cannot escape basic organic chemistry<\/a><br \/>\n<a href=\"http:\/\/scienceblogs.com\/gregladen\/2008\/06\/the_origin_of_life_on_earth_ne.php\">The Origin of Life on Earth: New Research<\/a><br \/>\n<a href=\"http:\/\/scienceblogs.com\/gregladen\/2007\/12\/origin_of_life.php\">Origin of Life (mica)<\/a><br \/>\n<a href=\"http:\/\/euchems2010.wordpress.com\/2010\/05\/31\/amino-acid-crystallisation-and-the-origin-of-life\/\">Amino acid crystallisation and the origin of life<\/a><br \/>\n<a href=\"http:\/\/bioenergyrus.blogspot.com\/2009\/05\/origin-of-life-rna.html\">The Origin of Life: RNA?<\/a><br \/>\n<a href=\"http:\/\/evolvefresno.blogspot.com\/2009\/03\/why-are-all-earthly-lifeforms-lefties.html\">Why are all earthly lifeforms lefties?<\/a><br \/>\n<a href=\"http:\/\/invaderxan.livejournal.com\/58769.html\">A Simple Kind of Life<\/a><br \/>\n<a href=\"http:\/\/evolvefresno.blogspot.com\/2008\/09\/life-universe-and-everything-else.html\">Life, The Universe, and Everything Else&#8230;<\/a><br \/>\n<a href=\"http:\/\/scienceblogs.com\/gregladen\/2008\/01\/avalon_and_the_origin_of_multi.php\">Avalon and the origin of multicellular life<\/a><br \/>\n<a href=\"http:\/\/scienceblogs.com\/gregladen\/2008\/06\/the_origin_of_life_on_earth_ne.php\">The Origin of Life on Earth: New Research<\/a><\/p>\n<p><em><strong>A sampling of mainly peer reviewed research and science editorial commentary related to the origin of life:<\/strong><\/em><\/p>\n<p>?Albar\u00e8de, F. (2009). Volatile accretion history of the terrestrial planets and dynamic implications. Nature, 461(7268), 1227-33. Macmillan Publishers Limited. All rights reserved. doi:10.1038\/nature08477<\/p>\n<p>Andersson, R. E. (1980). Microbial lipolysis at low temperatures. Applied and Environmental Microbiology, 39(1), 36-40. Retrieved from http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/6766702<\/p>\n<p>Anon. (2009). Darwin and microbiology. Nature reviews. Microbiology, 7(8), 546. Nature Publishing Group. doi:10.1038\/nrmicro2197<\/p>\n<p>Anon. (2010a). Napthalene, space &amp; life. Nature India. Nature Publishing Group. doi:10.1038\/nindia.2010.38<\/p>\n<p>Anon. (2010b). Hydrothermal Vents ? Ocean Policy ? Ancient Greeks. Scientific American, 302(4), 8-10. Scientific American, Inc. doi:10.1038\/scientificamerican0410-8<\/p>\n<p>Anon. (2010c). Probing the origin of life. Nature India. Nature Publishing Group. doi:10.1038\/nindia.2010.132<\/p>\n<p>Attwater, J., Wochner, A., Pinheiro, V. B., Coulson, A., &amp; Holliger, P. (2010). Ice as a protocellular medium for RNA replication. Nature communications, 1, 76. Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. doi:10.1038\/ncomms1076<\/p>\n<p>Baele, J.-M., Bouvain, F., De Jong, J., Matielli, N., Papier, S., &amp; Preat, A. (2008). Iron microbial mats in modern and phanerozoic environments. Proceedings of SPIE, 7097, 70970N-70970N-12. Spie. doi:10.1117\/12.801597<\/p>\n<p>Bakermans, C. (2008). Limits for microbial life at subzero temperatures. Psychrophiles from biodiversity to biotechnology, 17-28. Springer. Retrieved from http:\/\/www.springerlink.com\/index\/p121287548h670j7.pdf<\/p>\n<p>Ball, P. (2010). Some like it hot. Nature. Nature Publishing Group. doi:10.1038\/news.2010.590<\/p>\n<p>Barricelli, N. A. (1963). Numerical testing of evolution theories. Part II. Preliminary tests of performance, symbiogenesis and terrestrial life. Acta Biotheoretica, (16), 99 &#8211; 126. Retrieved from http:\/\/en.wikipedia.org\/wiki\/Genetic_algorithm<\/p>\n<p>Bedau, M., Church, G., Rasmussen, S., Caplan, A., Benner, S., Fussenegger, M., Collins, J., et al. (2010). Life after the synthetic cell. Nature, 465(7297), 422-4. Nature Publishing Group. doi:10.1038\/465422a<\/p>\n<p>Beer, D. D., &amp; K\u00fchl, M. (2001). INTERFACIAL MICROBIAL MATS AND BIOFILMS. Biofilms (pp. 374-394).<\/p>\n<p>Bergman, J. (2000). Why abiogenesis is impossible. Creation Research Society Quarterly, 36(4).<\/p>\n<p>Biello, D., &amp; Harmon, K. (2010). Tools for Life. Scientific American, 303(2), 17-18. Scientific American, Inc. doi:10.1038\/scientificamerican0810-17<\/p>\n<p>Bigot, Y., Samain, S., Aug\u00e9-Gouillou, C., &amp; Federici, B. A. (2008). Molecular evidence for the evolution of ichnoviruses from ascoviruses by symbiogenesis. BMC Evolutionary Biology, 8, 253. BioMed Central. Retrieved from http:\/\/www.pubmedcentral.nih.gov\/articlerender.fcgi?artid=2567993&amp;tool=pmcentrez&amp;rendertype=abstract<\/p>\n<p>Blaney, D. L. (2002). Using Mars&#8217;s Sulfur Cycle to Constrain the Duration and Timing of Fluvial Processes, 12p.<\/p>\n<p>Bottrell, S. H., &amp; Raiswell, R. (2000). Sulfur isotopes and microbial sulfur cycling in sediments. In R. E. Riding &amp; S. M. Awramik (Eds.), Microbial Sediments (pp. 96-104). Springer-Verlag.<\/p>\n<p>Bouougri, E. H., &amp; Porada, H. (2007). Siliciclastic biolaminites indicative of widespread microbial mats in the Neoproterozoic Nama Group of Namibia. Journal of African Earth Sciences, 48(1), 38-48. doi:10.1016\/j.jafrearsci.2007.03.004<\/p>\n<p>Bradley, A. S. (2009). Expanding the Limits of Life. Scientific American, 301(6), 62-67. Scientific American, Inc. doi:10.1038\/scientificamerican1209-62<\/p>\n<p>Caracciolo, A. B., Giuliano, G., Di Corcia, A., Crescenzi, C., &amp; Silvestri, C. (2001). Microbial degradation of terbuthylazine in surface soil and subsoil at two different temperatures. Bulletin of Environmental Contamination and Toxicology, 67(6), 815-820.<\/p>\n<p>Carrapi\u00e7o, F., &amp; Rodrigues, T. (2005). Symbiogenesis and the early evolution of life. Proc of SPIE, 5906, 242-245.<\/p>\n<p>Castenholz, R. W. (2009). Mats, Microbial. (J. Seckbach &amp; A. Oren, Eds.)Environmental Microbiology and Ecology, 14, 278-292. Springer Netherlands. doi:10.1007\/978-90-481-3799-2<\/p>\n<p>Cavicchioli, R. (2011). Archaea&#8211;timeline of the third domain. Nature reviews. Microbiology, 9(1), 51-61. Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. doi:10.1038\/nrmicro2482<\/p>\n<p>Chpt  Aravena, R., &amp; Mayer, B. (2010). Isotopes and Processes in the Nitrogen and Sulfur Cycles. Control, 203-246.<\/p>\n<p>Clarke, A. (2003). Evolution and low temperatures. Evolution.<\/p>\n<p>Claverie, J.-M., &amp; Ogata, H. (2009). 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Processes that constrain and facilitate the evolution of sexual dimorphism. The American Naturalist. doi:10.1086\/462434<\/p>\n<p>Devincenzi, D. L. (1983). Impact of solar system exploration on theories of chemical evolution and the origin of life.<\/p>\n<p>Dewitt, D. A. (2000). Theories of the Origin and Early Evolution of Life. National Geographic.<\/p>\n<p>Dominguez, G., Wilkins, G., &amp; Thiemens, M. H. (2011). The Soret effect and isotopic fractionation in high-temperature silicate melts. Nature, 473(7345), 70-3. Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. doi:10.1038\/nature09911<\/p>\n<p>Dugan, J. M., &amp; Altman, R. B. (2007). Using surface envelopes to constrain molecular modeling. Protein Science, 16(7), 1266-1273. Cold Spring Harbor Laboratory Press. Retrieved from http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17586766<\/p>\n<p>Dunker, A. K., &amp; Kriwacki, R. W. (2011). The Orderly Chaos of Proteins. Scientific American, 304(4), 68-73. Scientific American, Inc. doi:10.1038\/scientificamerican0411-68<\/p>\n<p>Dupraz, C., Reid, R. P., Braissant, O., Decho, A. W., Norman, R. S., &amp; Visscher, P. T. (2009). Processes of carbonate precipitation in modern microbial mats. Earth-Science Reviews, 96(3), 141-162. Elsevier B.V. doi:10.1016\/j.earscirev.2008.10.005<\/p>\n<p>Eisenreich, W., Dandekar, T., Heesemann, J., &amp; Goebel, W. (2010). Carbon metabolism of intracellular bacterial pathogens and possible links to virulence. Nature reviews. Microbiology, 8(6), 401-12. Nature Publishing Group. doi:10.1038\/nrmicro2351<\/p>\n<p>Eke, V. R., Cole, S., &amp; Frenk, C. S. (1996). Using the Evolution of Clusters to Constrain Omega. Retrieved from http:\/\/arxiv.org\/abs\/astro-ph\/9601088<\/p>\n<p>Eriksson, K. A., &amp; Simpson, E. L. (2000). Quantifying the oldest tidal record: The 3.2 Ga Moodies Group, Barberton Greenstone Belt, South Africa. Geology, 28(9), 831-834. doi:10.1130\/0091-7613(2000)028<0831:QTOTRT>2.3.CO;2<\/p>\n<p>Etxeberria, A., &amp; Ruiz-Mirazo, K. (2009). The challenging biology of transients. A view from the perspective of autonomy. EMBO reports, 10 Suppl 1(S1), S33-6. European Molecular Biology Organization. doi:10.1038\/embor.2009.154<\/p>\n<p>Farquhar, James, &amp; Wing, Boswell A. (2003). Multiple sulfur isotopes and the evolution of the atmosphere. Earth and Planetary Science Letters, 213(1-2), 1-13. doi:10.1016\/S0012-821X(03)00296-6<\/p>\n<p>Ferry, J. G., &amp; House, C. H. (2006). The stepwise evolution of early life driven by energy conservation. Molecular Biology and Evolution, 23(6), 1286-1292. Retrieved from http:\/\/mbe.oxfordjournals.org\/cgi\/content\/abstract\/23\/6\/1286<\/p>\n<p>Fletcher, S. P. (2009). Building blocks of life: Growing the seeds of homochirality. Nature chemistry, 1(9), 692-3. Nature Publishing Group. doi:10.1038\/nchem.455<\/p>\n<p>Follmann, H., &amp; Brownson, C. (2009). Darwin&#8217;s warm little pond revisited: from molecules to the origin of life. Die Naturwissenschaften, 96(11), 1265-1292. doi:10.1007\/s00114-009-0602-1<\/p>\n<p>Folsome, C. E. (1979). The origin of life a warm little pond. W H Freeman. Retrieved from http:\/\/www.worldcat.org\/isbn\/0716702940<\/p>\n<p>Friou, G. J. (1993). The early days of the antinuclear antibody story: where and how did it all start? Annales De Medecine Interne.<\/p>\n<p>Gall, J. C. (2001). Role of microbial mats. In D. E. G. Briggs &amp; P. R. Crowther (Eds.), (pp. 280-284). Blackwell Science.<\/p>\n<p>Gogarten, J. P. (1995). The early evolution of cellular life. TREE, 10, 147-151.<\/p>\n<p>Golding, S. D., Young, E., Duck, L. J., Baublys, K. A., &amp; Glikson, M. (2006). Multiple sulfur isotope constraints on microbial processes in Archaean seafloor environments. Geochimica et Cosmochimica Acta, 70(18, Supplement 1), A208. Retrieved from http:\/\/www.sciencedirect.com\/science\/article\/B6V66-4KPNB29-BG\/2\/bc958f74f3546305f290509d0780e079<\/p>\n<p>Goldman, N., Reed, E. J., Fried, L. E., William Kuo, I.-F., &amp; Maiti, A. (2010). Synthesis of glycine-containing complexes in impacts of comets on early Earth. Nature chemistry, 2(11), 949-54. Nature Publishing Group. doi:10.1038\/nchem.827<\/p>\n<p>Habicht, K. S., &amp; Canfield, Donald E. (1996). S isotope fractionation in modern microbial mats and the evolution of the S cycle.pdf. Nature, 382, 342-343.<\/p>\n<p>Harris, T. (2010). Evidence for RNA origins. Nature, 464(7288), 494-494. Nature Publishing Group. doi:10.1038\/464494a<\/p>\n<p>Hegde, N. R., Maddur, M. S., Kaveri, S. V., &amp; Bayry, J. (2009). Reasons to include viruses in the tree of life. Nature reviews. Microbiology, 7(8), 615; author reply 615. Nature Publishing Group. doi:10.1038\/nrmicro2108-c1<\/p>\n<p>Hessler, A. M., &amp; Lowe, D. R. (2006). Weathering and sediment generation in the Archean: An integrated study of the evolution of siliciclastic sedimentary rocks of the 3.2Ga Moodies Group, Barberton Greenstone Belt, South Africa. Precambrian Research, 151(3-4), 185-210. doi:10.1016\/j.precamres.2006.08.008<\/p>\n<p>Heubeck, C. (2009). An early ecosystem of Archean tidal microbial mats (Moodies Group, South Africa, ca. 3.2 Ga). Geology, 37(10), 931-934. doi:10.1130\/G30101A.1<\/p>\n<p>Hoehler, T. M., Bebout, B. M., &amp; Des Marais, D J. (2001). The role of microbial mats in the production of reduced gaes on the early Earth. Nature, 412, 324-327.<\/p>\n<p>Huang, F., Chakraborty, P., Lundstrom, C. C., Holmden, C., Glessner, J. J. G., Kieffer, S. W., &amp; Lesher, C. E. (2010). Isotope fractionation in silicate melts by thermal diffusion. Nature, 464(7287), 396-400. Macmillan Publishers Limited. All rights reserved. doi:10.1038\/nature08840<\/p>\n<p>J, M., &amp; Tully, J. C. (2008). Did life grind to a start? Nature, 452(March 13), 161-162.<\/p>\n<p>Johnson, C., Beard, B., Klein, C., Beukes, N., &amp; Roden, E. (2008). Iron isotopes constrain biologic and abiologic processes in banded iron formation genesis. Geochimica et Cosmochimica Acta, 72(1), 151-169. doi:10.1016\/j.gca.2007.10.013<\/p>\n<p>Johnston, D T, Farquhar, J, Wing, B A, Lyons, T., Kah, L., Strauss, H., &amp; Canfield, D E. (2005). Using the multiple isotopes of sulfur to constrain microbial processes in the Proterozoic ocean. Geochimica et Cosmochimica Acta, 69(10), A548-A548.<\/p>\n<p>Johnston, David T. (2011). Multiple sulfur isotopes and the evolution of Earth&#8217;s surface sulfur cycle. Earth-Science Reviews, 106(1-2), 161-183. Elsevier B.V. doi:10.1016\/j.earscirev.2011.02.003<\/p>\n<p>Kastelein, J. (2009). Abiogenesis Explained. Darwin.<\/p>\n<p>Katsnelson, A. (2010). Arsenic-eating microbe may redefine chemistry of life. Nature. Nature Publishing Group. doi:10.1038\/news.2010.645<\/p>\n<p>Kim, J., &amp; Winfree, E. 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But sometimes people say this, and sound quite innocent saying it, because they want to throw the average person off track and make them think that Evolutionary Biology &hellip; <a href=\"https:\/\/gregladen.com\/blog\/2011\/07\/30\/we-can-know-nothing-about-the\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">&#8220;We can know nothing about the origin of life&#8221;<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[2638],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p5fhV1-2BB","jetpack_likes_enabled":true,"_links":{"self":[{"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/posts\/10019"}],"collection":[{"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/comments?post=10019"}],"version-history":[{"count":0,"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/posts\/10019\/revisions"}],"wp:attachment":[{"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/media?parent=10019"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/categories?post=10019"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gregladen.com\/blog\/wp-json\/wp\/v2\/tags?post=10019"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}