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	Comments on: Why are some urinary tract infections chronic?	</title>
	<atom:link href="https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/feed/" rel="self" type="application/rss+xml" />
	<link>https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/</link>
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		<title>
		By: Maya		</title>
		<link>https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/#comment-521640</link>

		<dc:creator><![CDATA[Maya]]></dc:creator>
		<pubDate>Wed, 22 Jul 2015 09:54:50 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2010/08/12/why-are-some-urinary-tract-inf/#comment-521640</guid>

					<description><![CDATA[I also solved my UTIs naturally using a combination of various dietary, exercise, supplement, and life-style changes. I would not have been able to do it without helpful research like that is found in this article! Check out savvy.is/mayabenami for a personal consulting session tailored to your symptoms!]]></description>
			<content:encoded><![CDATA[<p>I also solved my UTIs naturally using a combination of various dietary, exercise, supplement, and life-style changes. I would not have been able to do it without helpful research like that is found in this article! Check out savvy.is/mayabenami for a personal consulting session tailored to your symptoms!</p>
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		<title>
		By: Greg Laden		</title>
		<link>https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/#comment-521639</link>

		<dc:creator><![CDATA[Greg Laden]]></dc:creator>
		<pubDate>Fri, 20 Aug 2010 01:12:10 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2010/08/12/why-are-some-urinary-tract-inf/#comment-521639</guid>

					<description><![CDATA[Edwin is a spammer, it turns out .  But I&#039;ll leave his comment in place and muck up his link. ]]></description>
			<content:encoded><![CDATA[<p>Edwin is a spammer, it turns out .  But I&#8217;ll leave his comment in place and muck up his link. </p>
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		<title>
		By: Stephanie Z		</title>
		<link>https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/#comment-521638</link>

		<dc:creator><![CDATA[Stephanie Z]]></dc:creator>
		<pubDate>Thu, 19 Aug 2010 20:48:44 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2010/08/12/why-are-some-urinary-tract-inf/#comment-521638</guid>

					<description><![CDATA[Before suggesting cranberry juice is a placebo, or that research on the topic isn&#039;t sufficient to answer the question, may I suggest you read the summary of research that Greg links to in comment #12?]]></description>
			<content:encoded><![CDATA[<p>Before suggesting cranberry juice is a placebo, or that research on the topic isn&#8217;t sufficient to answer the question, may I suggest you read the summary of research that Greg links to in comment #12?</p>
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		<title>
		By: Edwin		</title>
		<link>https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/#comment-521637</link>

		<dc:creator><![CDATA[Edwin]]></dc:creator>
		<pubDate>Thu, 19 Aug 2010 20:06:01 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2010/08/12/why-are-some-urinary-tract-inf/#comment-521637</guid>

					<description><![CDATA[Though if cranberry juice is a placebo, it might be worthwhile to ride the crest of its fad-dom, since without the vote of popular misconception, its efficacy (objective or not) may not last much longer.]]></description>
			<content:encoded><![CDATA[<p>Though if cranberry juice is a placebo, it might be worthwhile to ride the crest of its fad-dom, since without the vote of popular misconception, its efficacy (objective or not) may not last much longer.</p>
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		<title>
		By: Myotis rufopictus		</title>
		<link>https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/#comment-521636</link>

		<dc:creator><![CDATA[Myotis rufopictus]]></dc:creator>
		<pubDate>Thu, 19 Aug 2010 02:24:15 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2010/08/12/why-are-some-urinary-tract-inf/#comment-521636</guid>

					<description><![CDATA[I wouldn&#039;t trust any anecdotes of cranberry juice &quot;working&quot; for UTIs for the simple reason that it&#039;s become an article of folk wisdom so you would expect a strong placebo effect too. Also wouldn&#039;t trust any studies where the treatment group was drinking juice for the same reason so presumably that&#039;s why a number of studies used tablets or concentrates.]]></description>
			<content:encoded><![CDATA[<p>I wouldn&#8217;t trust any anecdotes of cranberry juice &#8220;working&#8221; for UTIs for the simple reason that it&#8217;s become an article of folk wisdom so you would expect a strong placebo effect too. Also wouldn&#8217;t trust any studies where the treatment group was drinking juice for the same reason so presumably that&#8217;s why a number of studies used tablets or concentrates.</p>
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		<title>
		By: Greg Laden		</title>
		<link>https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/#comment-521635</link>

		<dc:creator><![CDATA[Greg Laden]]></dc:creator>
		<pubDate>Sat, 14 Aug 2010 02:36:51 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2010/08/12/why-are-some-urinary-tract-inf/#comment-521635</guid>

					<description><![CDATA[Ah ... thanks for the  ... ah ... clarification.  ]]></description>
			<content:encoded><![CDATA[<p>Ah &#8230; thanks for the  &#8230; ah &#8230; clarification.  </p>
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		<title>
		By: becca		</title>
		<link>https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/#comment-521634</link>

		<dc:creator><![CDATA[becca]]></dc:creator>
		<pubDate>Fri, 13 Aug 2010 22:30:17 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2010/08/12/why-are-some-urinary-tract-inf/#comment-521634</guid>

					<description><![CDATA[Here, last part in picture: http://cheezburger.com/View/3857485056]]></description>
			<content:encoded><![CDATA[<p>Here, last part in picture: <a href="http://cheezburger.com/View/3857485056" rel="nofollow ugc">http://cheezburger.com/View/3857485056</a></p>
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		<title>
		By: becca		</title>
		<link>https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/#comment-521633</link>

		<dc:creator><![CDATA[becca]]></dc:creator>
		<pubDate>Fri, 13 Aug 2010 22:21:34 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2010/08/12/why-are-some-urinary-tract-inf/#comment-521633</guid>

					<description><![CDATA[AGHH! that&#039;ll teach me not to preview. Forgot the less than signs can look like tags. Hang on, I will graph...]]></description>
			<content:encoded><![CDATA[<p>AGHH! that&#8217;ll teach me not to preview. Forgot the less than signs can look like tags. Hang on, I will graph&#8230;</p>
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		<title>
		By: becca		</title>
		<link>https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/#comment-521632</link>

		<dc:creator><![CDATA[becca]]></dc:creator>
		<pubDate>Fri, 13 Aug 2010 22:19:40 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2010/08/12/why-are-some-urinary-tract-inf/#comment-521632</guid>

					<description><![CDATA[I&#039;ll try simpler. 

So here&#039;s the &quot;excellency of immune system&quot; rank order: CH3 strain with defunct TLR4 &lt; CH3 with intact TLR4 &lt; or = * B6 with intact TLR4 

*depending on the definition of excellency


And here&#039;s &quot;outcome of disease&quot; rank: CH3 with defunct TLR4, subset that are dead &lt; CH3 strain with intact TLR4 (chronically infected) &lt; CH3 strain with defunct TLR4, subset that are alive and recovered &lt; B6 mice with intact TLR4 (also alive and recovered) 
I grant you that the fact that the CH3 strain with defunct TLR4 &gt; the CH3 strain with intact TLR4 is counter-intuitive.

The fact that the dead mice are also those that have the least excellent immune system is intuitive. The fact that B6 mice do the best in both parameters is also intuitive, using the same premise that a robust inflammation helps fight infection (assuming you know anything about B/6 mice). ]]></description>
			<content:encoded><![CDATA[<p>I&#8217;ll try simpler. </p>
<p>So here&#8217;s the &#8220;excellency of immune system&#8221; rank order: CH3 strain with defunct TLR4 < CH3 with intact TLR4 < or = * B6 with intact TLR4 

*depending on the definition of excellency


And here's "outcome of disease" rank: CH3 with defunct TLR4, subset that are dead < CH3 strain with intact TLR4 (chronically infected) < CH3 strain with defunct TLR4, subset that are alive and recovered < B6 mice with intact TLR4 (also alive and recovered) 
I grant you that the fact that the CH3 strain with defunct TLR4 > the CH3 strain with intact TLR4 is counter-intuitive.</p>
<p>The fact that the dead mice are also those that have the least excellent immune system is intuitive. The fact that B6 mice do the best in both parameters is also intuitive, using the same premise that a robust inflammation helps fight infection (assuming you know anything about B/6 mice). </p>
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		<item>
		<title>
		By: Greg Laden		</title>
		<link>https://gregladen.com/blog/2010/08/12/why-are-some-urinary-tract-inf/#comment-521631</link>

		<dc:creator><![CDATA[Greg Laden]]></dc:creator>
		<pubDate>Fri, 13 Aug 2010 18:17:19 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2010/08/12/why-are-some-urinary-tract-inf/#comment-521631</guid>

					<description><![CDATA[Becca, given a mouse that is alleged to have a typical mouse immune system and a mouse that is alleged to have a genetically broken (or otherwise broken) immune system, I would say that a &quot;correct&quot; immune response in the latter and a &quot;bad&quot; immune response in the former verges on being a poster-child case for the word &quot;counterintuitive.&quot; 

The real situation on the ground is more complex than that.  That is usually the case when the word &quot;counterintuitive&quot; is used ... the word &quot;counterintuitive&quot; often precedes a further exploration of the situation that may lead to  better understanding and a re-evaluation of what is &quot;intuitive.&quot;  

It&#039;s kinda like a literary device.

]]></description>
			<content:encoded><![CDATA[<p>Becca, given a mouse that is alleged to have a typical mouse immune system and a mouse that is alleged to have a genetically broken (or otherwise broken) immune system, I would say that a &#8220;correct&#8221; immune response in the latter and a &#8220;bad&#8221; immune response in the former verges on being a poster-child case for the word &#8220;counterintuitive.&#8221; </p>
<p>The real situation on the ground is more complex than that.  That is usually the case when the word &#8220;counterintuitive&#8221; is used &#8230; the word &#8220;counterintuitive&#8221; often precedes a further exploration of the situation that may lead to  better understanding and a re-evaluation of what is &#8220;intuitive.&#8221;  </p>
<p>It&#8217;s kinda like a literary device.</p>
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