https://gregladen.com/blog/2008/05/20/resurrection-of-dna-function-f/ Tue, 20 May 2008 13:31:01 +0000 hourly 1 https://wordpress.org/?v=6.4.6 https://gregladen.com/blog/2008/05/20/resurrection-of-dna-function-f/#comment-8367 Tue, 20 May 2008 13:31:01 +0000 http://scienceblogs.com/gregladen/2008/05/20/resurrection-of-dna-function-f/#comment-8367 Technically, that research Ross points to (Römpler H, et. al (2006) Nuclear Gene Indicates Coat-Color Polymorphism in Mammoths, Science 313, p. 6 (http://www.sciencemag.org/cgi/content/abstract/sci;313/5783/62) is in vitro, not whole organisms, which I believe the authors of this PLoS paper are claiming.

]]> https://gregladen.com/blog/2008/05/20/resurrection-of-dna-function-f/#comment-8366 Tue, 20 May 2008 12:47:12 +0000 http://scienceblogs.com/gregladen/2008/05/20/resurrection-of-dna-function-f/#comment-8366 Im confused as to why they are claiming this is the first instance of the “resurrection” of an extinct gene. Work by Rompler et al in Science last year inserted the Mammoth version of the MC1R gene into a mouse model and showed that it had the phenotypic effect of blondeness. That work actually led to some interesting data on phenotype in living Mammoth, whereas this work appears to be pretty useless.

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