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	<title>
	Comments on: New Twist in microRNA biology	</title>
	<atom:link href="https://gregladen.com/blog/2008/01/11/new-twist-in-microrna-biology/feed/" rel="self" type="application/rss+xml" />
	<link>https://gregladen.com/blog/2008/01/11/new-twist-in-microrna-biology/</link>
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	<lastBuildDate>Fri, 11 Jan 2008 23:26:42 +0000</lastBuildDate>
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		<title>
		By: OneRandomScientist		</title>
		<link>https://gregladen.com/blog/2008/01/11/new-twist-in-microrna-biology/#comment-2766</link>

		<dc:creator><![CDATA[OneRandomScientist]]></dc:creator>
		<pubDate>Fri, 11 Jan 2008 23:26:42 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2008/01/11/new-twist-in-microrna-biology/#comment-2766</guid>

					<description><![CDATA[So microRNA genes can overlap on different strands?  That&#039;s pretty cool, but I don&#039;t think quite &quot;never even been hypothesized&quot; level...]]></description>
			<content:encoded><![CDATA[<p>So microRNA genes can overlap on different strands?  That&#8217;s pretty cool, but I don&#8217;t think quite &#8220;never even been hypothesized&#8221; level&#8230;</p>
]]></content:encoded>
		
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		<title>
		By: rpenner		</title>
		<link>https://gregladen.com/blog/2008/01/11/new-twist-in-microrna-biology/#comment-2765</link>

		<dc:creator><![CDATA[rpenner]]></dc:creator>
		<pubDate>Fri, 11 Jan 2008 19:38:10 +0000</pubDate>
		<guid isPermaLink="false">http://scienceblogs.com/gregladen/2008/01/11/new-twist-in-microrna-biology/#comment-2765</guid>

					<description><![CDATA[&lt;blockquote&gt;about as surprising as discovering that a mold used to cast a metal tool can also serve as a tool itself&lt;/blockquote&gt;Not at all suprising if either: &lt;ol&gt;&lt;li&gt;You have a complete neophyte designer who thinks that in addition to having a need for a tool cast, he wants to get at the same time a file to sharpen it and doesn&#039;t care how it fits in the hand. The centuries of grief the abandonment of K.I.S.S. engineering principles will be directly attributable to such a unqualified designer. &lt;b&gt;Or...&lt;/b&gt;&lt;/li&gt;&lt;li&gt;Things like the mold are developed piecewise by unintellegent agents from ancestor blobs and templates for blobs that serve a useful function are communicated to other agents for templates to continue the common descent with undirected changes accumulating over time. In such a model, if the blob has two functions, that makes it likely to outcompete a &quot;designed&quot; alternative which neglects one function for only modest gains for the other function.&lt;/li&gt;&lt;/ol&gt;]]></description>
			<content:encoded><![CDATA[<blockquote><p>about as surprising as discovering that a mold used to cast a metal tool can also serve as a tool itself</p></blockquote>
<p>Not at all suprising if either: </p>
<ol>
<li>You have a complete neophyte designer who thinks that in addition to having a need for a tool cast, he wants to get at the same time a file to sharpen it and doesn&#8217;t care how it fits in the hand. The centuries of grief the abandonment of K.I.S.S. engineering principles will be directly attributable to such a unqualified designer. <b>Or&#8230;</b></li>
<li>Things like the mold are developed piecewise by unintellegent agents from ancestor blobs and templates for blobs that serve a useful function are communicated to other agents for templates to continue the common descent with undirected changes accumulating over time. In such a model, if the blob has two functions, that makes it likely to outcompete a &#8220;designed&#8221; alternative which neglects one function for only modest gains for the other function.</li>
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