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	Comments on: More&#8221;Junk&#8221;DNA is Not	</title>
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	<lastBuildDate>Wed, 12 Dec 2007 16:56:50 +0000</lastBuildDate>
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		By: qetzal		</title>
		<link>https://gregladen.com/blog/2007/12/12/more-junk-dna-is-not/#comment-1737</link>

		<dc:creator><![CDATA[qetzal]]></dc:creator>
		<pubDate>Wed, 12 Dec 2007 16:56:50 +0000</pubDate>
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					<description><![CDATA[One possible criticism of their work: is it possible that a particular isolated sequence might affect expression of GFP (or whatever they used), yet NOT be important for regulating phox2b?I vaguely recall studies claiming that if you insert completely random bits of DNA upstream of a promoter-less reporter gene, a surprisingly high fraction will result in detectable expression.]]></description>
			<content:encoded><![CDATA[<p>One possible criticism of their work: is it possible that a particular isolated sequence might affect expression of GFP (or whatever they used), yet NOT be important for regulating phox2b?I vaguely recall studies claiming that if you insert completely random bits of DNA upstream of a promoter-less reporter gene, a surprisingly high fraction will result in detectable expression.</p>
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