Comments on: More “Junk” DNA is Not https://gregladen.com/blog/2007/12/12/more-junk-dna-is-not-2/ Wed, 12 Dec 2007 16:56:50 +0000 hourly 1 https://wordpress.org/?v=6.4.8 By: qetzal https://gregladen.com/blog/2007/12/12/more-junk-dna-is-not-2/#comment-550423 Wed, 12 Dec 2007 16:56:50 +0000 http://scienceblogs.com/gregladen/2007/12/12/more-junk-dna-is-not/#comment-550423 One possible criticism of their work: is it possible that a particular isolated sequence might affect expression of GFP (or whatever they used), yet NOT be important for regulating phox2b?

I vaguely recall studies claiming that if you insert completely random bits of DNA upstream of a promoter-less reporter gene, a surprisingly high fraction will result in detectable expression.

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