MIT researchers have successfully treated mice with sickle-cell anemia in a process that begins by directly reprogramming the mice’s own cells to an embryonic-stem-cell-like state, without the use of eggs.This is the first proof-of-principle of therapeutic application in mice of directly reprogrammed induced pluripotent stem (IPS) cells, which recently have been derived in mice as well as humans.”This demonstrates that IPS cells have the same potential for therapy as embryonic stem cells, without the ethical and practical issues raised in creating embryonic stem cells,” said MIT biology professor Rudolf Jaenisch, a member of the Whitehead Institute for Biomedical Research.[Source]

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